ID A4X456_SALTO Unreviewed; 339 AA.
AC A4X456;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ABP53656.1};
GN OrderedLocusNames=Strop_1186 {ECO:0000313|EMBL:ABP53656.1};
OS Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS 105044 / CNB-440).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Salinispora.
OX NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP53656.1, ECO:0000313|Proteomes:UP000000235};
RN [1] {ECO:0000313|Proteomes:UP000000235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC {ECO:0000313|Proteomes:UP000000235};
RX PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA Jensen P.R., Moore B.S.;
RT "Genome sequencing reveals complex secondary metabolome in the marine
RT actinomycete Salinispora tropica.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
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DR EMBL; CP000667; ABP53656.1; -; Genomic_DNA.
DR RefSeq; WP_011905088.1; NC_009380.1.
DR AlphaFoldDB; A4X456; -.
DR STRING; 369723.Strop_1186; -.
DR KEGG; stp:Strop_1186; -.
DR PATRIC; fig|369723.5.peg.1208; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR Proteomes; UP000000235; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000235};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 316..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 339 AA; 36551 MW; D44A68080D94CD3B CRC64;
MQRPTIADIA RRAGVSKGAV SFALNGRPGV SAATRARILR VAEEINWRPH SAARALGGAR
ADAVGLVIAR PARTLGVEPF FARLLSGLQA EFSSQSIALH LMIVEDTQAE IEIYRRWVSE
RRVDGLVLID LKVRDPRIAV VEQLGIPAVV VGGPGRHGRV SSVWADDRTA MLSAVEYLAV
LGHTRIAHVS GLPEFQHTQR RSRALRDAAT RLTLPRARSL HTDFSDAQGA AATRKLLAGA
NRPSAIIFDS DLMAVAGLGV ALEMGVAVPH ELSIISFDDS VLAQLTHPSL TALSRDTYRF
GVQAAQAMMA VLADPTKTKN HKTETPRLIA RESTSPTRN
//
