ID A4X8Y2_SALTO Unreviewed; 635 AA.
AC A4X8Y2;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Regulatory protein, TetR {ECO:0000313|EMBL:ABP55332.1};
GN OrderedLocusNames=Strop_2892 {ECO:0000313|EMBL:ABP55332.1};
OS Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS 105044 / CNB-440).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Salinispora.
OX NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP55332.1, ECO:0000313|Proteomes:UP000000235};
RN [1] {ECO:0000313|Proteomes:UP000000235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC {ECO:0000313|Proteomes:UP000000235};
RX PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA Jensen P.R., Moore B.S.;
RT "Genome sequencing reveals complex secondary metabolome in the marine
RT actinomycete Salinispora tropica.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
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DR EMBL; CP000667; ABP55332.1; -; Genomic_DNA.
DR AlphaFoldDB; A4X8Y2; -.
DR STRING; 369723.Strop_2892; -.
DR KEGG; stp:Strop_2892; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_430756_0_0_11; -.
DR Proteomes; UP000000235; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000000235};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 428..488
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 451..470
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 65168 MW; 54F80F5AD662D30F CRC64;
MWGTCSTCSS CRDRRPLARP GGAPAGGAGR GPAGARPAGA GRRPARRRGR RPGRRRAERV
GPPDGLVRVR AGARGLPGDT GRPVAGLGGA LGRAAGAATP VPAPAPCAGP AALARRGGDA
GAAPARPARA ALAGGRGGGA ARRGSPRAAA RPVERRRPAP AGPGAAPGRR LRHAAAVARA
RCRLRAGWRL VVPADRAVPG RPPGPGPGRA AGGHPGAHRG TRVRRTGRRY TVPVGSAGPA
RQHRALRVPG EPDAGRRGCP APTDRGGHPQ HRAAGRDRPR RGLQRGRGPV ARGARPGPPA
RGRLAGLATG GTRLVSALAA VRLGRARGVA ARCRVRAVRG GLAVPGAAGP SEPDDRARQG
GAAAGRVHGR RRPLGTGGGR RRPCSRTPQP RLGLGGLDPA AARHDLAGAT GDGCDDRTAT
PGGRRAMSDT KRRLLDGTLA AIRQHGIAGV SARTIATAAG VNQALVFYHF GTLDELLAAA
CRTGTAERVA HWSARLRQVG SLRELLDVGR GLHAKERELG NVSVLAQMLA GAQADERLAA
PTAESLQLWV DEIELVLRRL LAGSPFAEIA DVPGLARAVS AAFIGLELYD GVDRPSAERA
IEALDQLAVL IEIVDDLGPI ARRALHNKIS KATRR
//
