ID A4YFG2_METS5 Unreviewed; 488 AA.
AC A4YFG2;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=4-hydroxyphenylacetate 3-monooxygenase oxygenase component {ECO:0000313|EMBL:ABP95164.1};
DE EC=1.14.14.9 {ECO:0000313|EMBL:ABP95164.1};
GN OrderedLocusNames=Msed_0996 {ECO:0000313|EMBL:ABP95164.1};
OS Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS / TH2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP95164.1, ECO:0000313|Proteomes:UP000000242};
RN [1] {ECO:0000313|EMBL:ABP95164.1, ECO:0000313|Proteomes:UP000000242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC {ECO:0000313|Proteomes:UP000000242};
RX PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT archaeon Metallosphaera sedula provides insights into bioleaching-
RT associated metabolism.";
RL Appl. Environ. Microbiol. 74:682-692(2008).
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DR EMBL; CP000682; ABP95164.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YFG2; -.
DR STRING; 399549.Msed_0996; -.
DR KEGG; mse:Msed_0996; -.
DR eggNOG; arCOG02143; Archaea.
DR HOGENOM; CLU_023920_2_1_2; -.
DR Proteomes; UP000000242; Chromosome.
DR GO; GO:0052881; F:4-hydroxyphenylacetate 3-monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:ABP95164.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ABP95164.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000242}.
FT DOMAIN 5..269
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 281..474
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
SQ SEQUENCE 488 AA; 56661 MW; D0AECCC2C19D3BAB CRC64;
MIRKGSDYIE SISKNPPVTY YEGEVVSDVV NHPAFRIPVK TVASYYDLHW KVDGLRVYNR
DVGEETSISL VRPRSKEDLL KLGEGLVKIY EFYRGFFGRS PDYMNLWTMV FFAHAEDYFG
KHFGSRFMEN AMEIYRESTR KDHFYTHAIV APMYDRSRPP SQWEDPYIQI GITEERPEGV
VVRGAAMICT AGPYAEMLWY LPNMRRDSDP RYALYFSIPT TTKGVRFIAR RGFQPREGGE
FEYPISSRWD EADAILVLDN VLVPWDRIIF FKKPELIEDL MWHTVGLRGW FNWHFMIQHY
TRLKFLAGLA MTITEAAGTS TFINVQEKIG EILLYVALNE AALYGSVARA QELPNIVRPD
PYISISASHF NMKAVPRANE ILRLISAGSS IPIPAGAKDF TNPEERAYLE KYMAMKGFDA
LERVKTFNLL WDVIGSEVGM RYEQYDRFSR GDPTIRWAQT YTEVFRDRRN EFVKLVKEIL
DQMPNPKA
//
