ID A4YPA7_BRASO Unreviewed; 873 AA.
AC A4YPA7;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=Putative transcriptional regulatory protein GntR family, with an PLP-dependent aminotransferase, a MOSC and an rubredoxin domain putative modular protein {ECO:0000313|EMBL:CAL75733.1};
GN OrderedLocusNames=BRADO1862 {ECO:0000313|EMBL:CAL75733.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL75733.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL75733.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CU234118; CAL75733.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YPA7; -.
DR KEGG; bra:BRADO1862; -.
DR eggNOG; COG1167; Bacteria.
DR eggNOG; COG3217; Bacteria.
DR HOGENOM; CLU_328918_0_0_5; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd00730; rubredoxin; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 2.40.33.20; PK beta-barrel domain-like; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR005302; MoCF_Sase_C.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR011037; Pyrv_Knase-like_insert_dom_sf.
DR InterPro; IPR024934; Rubredoxin-like_dom.
DR InterPro; IPR024935; Rubredoxin_dom.
DR InterPro; IPR018527; Rubredoxin_Fe_BS.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF03473; MOSC; 1.
DR Pfam; PF00301; Rubredoxin; 1.
DR PRINTS; PR00035; HTHGNTR.
DR PRINTS; PR00163; RUBREDOXIN.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF50800; PK beta-barrel domain-like; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF57802; Rubredoxin-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
DR PROSITE; PS51340; MOSC; 1.
DR PROSITE; PS00202; RUBREDOXIN; 1.
DR PROSITE; PS50903; RUBREDOXIN_LIKE; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:CAL75733.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:CAL75733.1};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 13..81
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT DOMAIN 651..795
FT /note="MOSC"
FT /evidence="ECO:0000259|PROSITE:PS51340"
FT DOMAIN 813..864
FT /note="Rubredoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50903"
FT REGION 506..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 873 AA; 94926 MW; F2B77F26994614F3 CRC64;
MQLSVLLDRS RPETLTAQMV DQIRDAIRSA RIAPGARLPS SRLLSDQLNV SRNTIVRAYD
LLIMEGLVES RPASGVYVTE RLPPAAREPG NVTRLPARTL MPMPLRAARG PASSHPPQKR
LLHDFCPGRP AAELFPIKAW RRLLTHHLPH GGSVGLTTDG DVAGVPALRT AIAQHLAAAR
GIAADPSRIV IVSGVQDAVT LMSRLFLARG QLAVVEDPGA EGPALSFEAA GAELGFVGVD
QDGLLPDELP QRPASLLYAT PAHQFPTGAT LSARRRAELI DWARRFGCYL IEDDYDCDIR
YHGSHLPPLA ALAPDCTVHV GSFTASLGAG LRLGYMVVPE PIAAAVIAEK TLLTHGSSWL
EQATLADFMH SGAYANHLLR VRAHYRDSRD ALIAALRGHF GDVSVDGEAG GLHLIWHLPP
GIPDAVTVEA LARRARIGVY SLGSARVRFR QRGALTSRAL MLGYAALSPR QIEKGIARLS
DVIDDAIDDP ATDMSALFAD QFAPPRVPAP EPKLAPRHRQ QPALRRPREP RAMSTPSFAR
QGVAPMPVLT SIYRYPIKGL SAQPLSSVML EAKKPFPHDR VFALVRPGAP YDLAQPRWGK
KGLFVMLMLE ETLARVRTSL DVETSRLVVT QDNHALITAD LNDAGGRSAL EQLIWQLVPQ
LRGAPTLVRT RDGHFMDKPD NVISLINLAT LRSLESQWGI SIDPLRFRAN LYIDGARPWE
EFDWVGHDIR IGDALFRVDR RNGRCGATNV DPHTGRRDLD IPGSLRAAFG HKELGVYLIA
REGGEVTVGQ QVTPPAVPQS VSYHSRLVPP SGTQPFICRG CYYIYDPAAG QPEQGVAPGT
AFAAIPLSWR CPDCGTDKST FRPHLPGTRS AVP
//
