ID A4YWH4_BRASO Unreviewed; 441 AA.
AC A4YWH4;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Nitrilotriacetate monooxygenase component A (NTA monooxygenase component A) (NTA-MO A) {ECO:0000313|EMBL:CAL78250.1};
DE EC=1.14.13.- {ECO:0000313|EMBL:CAL78250.1};
GN Name=ntaA {ECO:0000313|EMBL:CAL78250.1};
GN OrderedLocusNames=BRADO4512 {ECO:0000313|EMBL:CAL78250.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL78250.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL78250.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- SIMILARITY: Belongs to the NtaA/SnaA/DszA monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00033748}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU234118; CAL78250.1; -; Genomic_DNA.
DR RefSeq; WP_011927360.1; NC_009445.1.
DR AlphaFoldDB; A4YWH4; -.
DR STRING; 114615.BRADO4512; -.
DR KEGG; bra:BRADO4512; -.
DR eggNOG; COG2141; Bacteria.
DR HOGENOM; CLU_022256_1_2_5; -.
DR OrthoDB; 9779442at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd01095; Nitrilotriacetate_monoxgenase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR016215; NTA_MOA.
DR NCBIfam; TIGR03860; FMN_nitrolo; 1.
DR PANTHER; PTHR30011; ALKANESULFONATE MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR30011:SF16; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR PIRSF; PIRSF000337; NTA_MOA; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000337-1};
KW FMN {ECO:0000256|PIRSR:PIRSR000337-1};
KW Monooxygenase {ECO:0000313|EMBL:CAL78250.1};
KW Oxidoreductase {ECO:0000313|EMBL:CAL78250.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994}.
FT DOMAIN 19..385
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT BINDING 57
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 99
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 149
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 153
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 224
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
SQ SEQUENCE 441 AA; 48499 MW; F5DC0F81FE760B6D CRC64;
MAPRQLKLGA FMRPVSIHTG AWRYPGAWPD ANFNFAHLKQ LIRKLEAGKF DAFFMADHLA
VLNMPINALK RSHTVTSFEP FTLLSALSAV TENIGLIATG STTFDEPYHV ARRFASLDHI
SGGRAGWNIV TTSNPDAALN FGLDDHMEHA ERYKRAREFY DVVTGLWDSF ADDAFVRDVE
SGLFFDPDKM HVLDHKGKYL KVRGPLNIAR PVQGWPVIVQ AGASEDGKQL AAETAEAVFT
GGGSLADGQK LYADIKGRME KVGRDPDHLK ILPGAFVVVG DSDAEAKEKR ALLDSKVHYD
SAIASLSVIL GTDASGFDPD GQLPDIPETN ASKSGRQRLV DVAARDKLTV RQLAQRVGGY
GGLAFVGTAK TIADQMQDWL ESRGSDGFNI MFPFLPAGLD DFVDKVIPEL QRRGIFRREY
EGPTLRDNLG LPRPKNRFFP G
//
