ID A4Z139_BRASO Unreviewed; 581 AA.
AC A4Z139;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Putative Adenylate cyclase {ECO:0000313|EMBL:CAL79865.1};
DE EC=4.6.1.1 {ECO:0000313|EMBL:CAL79865.1};
GN OrderedLocusNames=BRADO6220 {ECO:0000313|EMBL:CAL79865.1};
OS Bradyrhizobium sp. (strain ORS 278).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL79865.1, ECO:0000313|Proteomes:UP000001994};
RN [1] {ECO:0000313|EMBL:CAL79865.1, ECO:0000313|Proteomes:UP000001994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
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DR EMBL; CU234118; CAL79865.1; -; Genomic_DNA.
DR RefSeq; WP_012029751.1; NC_009445.1.
DR AlphaFoldDB; A4Z139; -.
DR STRING; 114615.BRADO6220; -.
DR KEGG; bra:BRADO6220; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG5616; Bacteria.
DR HOGENOM; CLU_019981_0_0_5; -.
DR OrthoDB; 9807521at2; -.
DR Proteomes; UP000001994; Chromosome.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CAL79865.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001994}.
FT DOMAIN 7..121
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 581 AA; 64440 MW; 45C38F5CB15285F9 CRC64;
MERRLAAILC ADVAGYSRMM GIDEAGTHAA FKAHRSAIHP IILNHAGRIV KHTGDGFLLE
FANAASAIQF GVEMQCLMAE RNAHLPADRN MRFRLGIHRG EVTIDDGEAF GDGINVAVNL
ESIATPGGVA VSGRAYEEAS LQLPVNLTLA GSFQFGNFQE PVQAWTWEPD SDGAFGSQKN
ATSLPAQYRT AIVGVLPFAN LSDGPDEYLA DGLADDLIHA LSLQSFFRVL SRTSTFRFRD
RDLNLRLIAR EIDATYLIQG TVRRSHDKIR VTAELIVPES GAQLWTGRYD RDLGDLFAMQ
DEITTSLCAA LMPEIYRVEA SVPFRSPATN PTAWDRFLRG LSHYYRPTKA DYEVAIALFR
EAISLDPSLG IAHAYLATIL MQGISFGWIK GSRELWDEAK SLALDSVRLD PRSSFAYAIL
AFVQAMQGAH DDGMKAARKA TELNAYDMGA RGVLGLCHMV SGEHQLAIDQ FSIAAQRGNS
DPRYQWPALN AYSHYLIGRY EAALSWAREE LLLYPNHLQA LMVRAATLAQ LGDTDQARAA
IRGMREQYPW LTLDRHVKNI RWKNRADLDH YRDGLIKAGL I
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