ID A5A7P1_TRISC Unreviewed; 295 AA.
AC A5A7P1;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Tumor necrosis factor receptor superfamily, member 6b {ECO:0000313|EMBL:BAF62126.1};
GN Name=TNFRSF6B {ECO:0000313|EMBL:BAF62126.1};
OS Triakis scyllium (Banded houndshark) (Hemigaleus pingi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Triakidae;
OC Triakis.
OX NCBI_TaxID=30494 {ECO:0000313|EMBL:BAF62126.1};
RN [1] {ECO:0000313|EMBL:BAF62126.1}
RP NUCLEOTIDE SEQUENCE.
RA Inoue Y., Morinaga A., Saito T., Endo M., Haruta C., Nakai T., Moritomo T.,
RA Nakanishi T.;
RT "Molecular cloning and expression analysis of banded dogfish (Triakis
RT scyllia) TNF decoy receptor 3 cDNAs.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; AB282596; BAF62126.1; -; Genomic_DNA.
DR AlphaFoldDB; A5A7P1; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd10575; TNFRSF6B; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR034023; TNFRSF6B_N.
DR PANTHER; PTHR23097; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR23097:SF116; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00206}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Receptor {ECO:0000313|EMBL:BAF62126.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..295
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002678821"
FT DOMAIN 63..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 63..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REGION 245..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 64..79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 86..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 295 AA; 34076 MW; 15C675B3CD731493 CRC64;
MIFKCVISIL LIENVRSFWL ETVKPTYKRR DAITGQMVTC EQCPPGTFVK EHCTSIQPTM
CERCPDLHYT QYWNYLQKCR YCNVFCVDYQ YEKHQCNSTH NRVCECQPGY YLEFEFCLKQ
SSCPYGAGVI KMGTPYSDTN CEPCSHGYFS PSVSSSEPCF IHTNCTKEGL EVNVPGNQYH
DTLCTSCKKY DASGILDDSA LSPCNEAIIQ FVAYQKIPLK KLTRFLSLLQ IEEAKKLSKE
LRTHNKHMMH EKLRSSSTEM ERRYQEKPSN GKNLANNEKS KVEECCKKCP RAFYA
//
