ID   A5AHN2_VITVI            Unreviewed;       803 AA.
AC   A5AHN2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_026520 {ECO:0000313|EMBL:CAN82166.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN82166.1};
RN   [1] {ECO:0000313|EMBL:CAN82166.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM426994; CAN82166.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5AHN2; -.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR005162; Retrotrans_gag_dom.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR24559:SF433; RNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF03732; Retrotrans_gag; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
FT   DOMAIN          33..124
FT                   /note="Retrotransposon gag"
FT                   /evidence="ECO:0000259|Pfam:PF03732"
FT   DOMAIN          441..539
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
FT   DOMAIN          553..628
FT                   /note="Reverse transcriptase/retrotransposon-derived
FT                   protein RNase H-like"
FT                   /evidence="ECO:0000259|Pfam:PF17919"
FT   REGION          209..252
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   803 AA;  91915 MW;  4018C443812FA07A CRC64;
     MDRENPYQHI KEFEEVCNTF REGGASIDLM RLKLFPFTLK DKAKVWLNSL RPKSIRSWND
     LQPEFLKKFF STHRTNGLKR QISNFSAKEN EKFYEYWERY MEAINAFPHH GFDTWLLVSY
     FYDGKVNALI MQEMTNRDRR MDRTHNDLSQ KIDNLQYQIS RLTNLNTVQE KGKFPSQPHQ
     NPKAIHEVEA QEGESSQMRE FKAVITLRSG KEVDLHTPKP EQKPEQEPEQ ELETEVENEK
     REENKGKKIG SSTKKADLEA KDLYTIKRGL NVSKKAFLTE QVSSIIQCKS LVKYKDSGCP
     SISVMIGETC VEKALLDLGA SVNLLPYSVY KQLGLGELNP ISITLSLVDR SVKIPRGMIK
     DVLVQVDKFY YPVDFFVLDM DPVTKGTNYI PIILGRPFLT TSNAIINYSP WVSPTQVVPK
     KSGITVVQND KGEEVSTRLT SGIFQIEIAI EDQEKTTFTC PFEIYAYKRM SFGLCNAPAT
     FQRCMLSIFI DMVERIMEVF MDDITVYGTV LNRCIEKDLV LNWEKCHFMV PQGIVLGHII
     SSQGIEVDKA KVALIFKLPS PTTIKRMMCD AGDFAIGVVL GKIEDGKPYV IYYASKTLNE
     EQRNYTTAKK ELLAVVFALD KFRAYLIKDK KGVENVVADH LSRLAIAHTS HNLPINDDFP
     EESLMLIEAA PWYVHIANYL VIGEVPRSQE SNASNRVRFG AEMRKIWPLE DNCAKLVRNS
     HNTFSLCELV RSLCELVRSL CETRTTPSAC AKLAQHSHNI FTAHAWCKFS SVPPTPREIF
     SFRYFCINFL SSPCNPPIIR FLS
//