ID   A5AJC9_VITVI            Unreviewed;      1199 AA.
AC   A5AJC9;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_010202 {ECO:0000313|EMBL:CAN60302.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN60302.1};
RN   [1] {ECO:0000313|EMBL:CAN60302.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM428088; CAN60302.1; -; Genomic_DNA.
DR   ExpressionAtlas; A5AJC9; baseline and differential.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1228; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT   DOMAIN          42..84
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          121..279
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   UNSURE          983
FT                   /note="I or L"
FT                   /evidence="ECO:0000313|EMBL:CAN60302.1"
SQ   SEQUENCE   1199 AA;  136857 MW;  29D64D0E4B1191A3 CRC64;
     MVVVEAFLSS LFEVVLDKLV ATPLLDYARR IKVDTAVLPG VEQIREEAVK XWVDDLKALA
     YDIEDVLDEF DMEAKRCSWV QGPQTSTSKV XKLIPSFHPS DKAEFYGRDG DKEKIMELLL
     SDEIATADKV QKKLNGKRFF LVLDDIWNED PNSWGTLQAP FRNGAQGSVV MVTTRLEDVA
     SIMRTTSSHH LSKLSDEDCW SLFAGIAFEN VTPDARQNLE PIGRKIIKKC DGLPLAANTL
     AGLLRCKQDE KTWKDMLNSE IWDLRTEQSR ILPALHLSYH YLPTKVKQCF AYCSIFPKDY
     EFQKEELILL WMAQGLVGSL KGGETMEDVG EICFQNLLSR SFFQQSGHNK SMFVMHDLIH
     DLAQFVSGEF CFRLEMGQQK NVSKNARHFS YDRELFDMSK KFDPLRDIDK LRTFLPLSKP
     GYQLPCYLGD KVLHDVLPKF RCMRVLSLSY YNITYLPDSF GNLKHLRYLN LSNTKIRKLP
     KSIGMLLNLQ SLILSECRWL TELPAEIGKL INLRHLDIPK TKIEGMPMGI NGLKDLRMLT
     TFVVGKHGGA RLGELRDLAH LQGALSILNL QNVENATEVN LMKKEDLDDL VFAWDPNAIV
     GDLEIQTKVL EKLQPHNKVK RLIIECFYGI KFPKWLEDPS FMNLVFLQLR DCKNCLSLPP
     LGQLQSLKDL CIVKMDDVRK VGVELYGNSY CSSTSIKPFG SLEILRFEEM LEWEEWVCRG
     VEFPCLKELY IKKCPNLKKD LPEHLPKLTE LEISKCEQLV CCLPMAPSIR RLELKECDDV
     VVRSAGSLTS LAYLTIRNVC KIPDELGQLN SLVQLCVYRC PELKEIPPIL HSLTSLKNLN
     IENCESLASF PEMALPPMLE SLEIRACPTL ESLPEGMMQN NTTLQCLEIW HCGSLRSLPR
     DIDSLKRLVI CECKKLELAL HEDMTHNHYA SLTKFDITSC CDSLTSFPLA SFTKLETLDF
     FNCGNLESLY IPDGLHHVDL TSXQSLEIRN CPNLVSFPRG GLPTPNLRRL WILNCEKLKS
     LPQGMHTLLT SLQHLHISNC PEIDSFPEGG LPTNLSELDI RNCNKLVANQ MEWGLQTLPF
     LRTLTIEGYE NERFPEERFL PSTLTSLEIR GFPNLKSLDN KGLQHLTSLE TLRIRECGNL
     KSFPKQGLPS SLSSLYIEEC PLLNKRCQRD KGKEWPKISH IPCIAFDQYD PETIWKMGR
//