ID A5AMA8_VITVI Unreviewed; 959 AA.
AC A5AMA8;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=VITISV_043726 {ECO:0000313|EMBL:CAN64711.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN64711.1};
RN [1] {ECO:0000313|EMBL:CAN64711.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; AM430024; CAN64711.1; -; Genomic_DNA.
DR ExpressionAtlas; A5AMA8; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF601; GLUTAMATE RECEPTOR 3.2; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00062; PBPb; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 625..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 861..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 503..843
FT /note="Solute-binding protein family 3/N-terminal"
FT /evidence="ECO:0000259|SMART:SM00062"
FT DOMAIN 505..842
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 921..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 791..845
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 959 AA; 106400 MW; 8BDB7428A0F46F96 CRC64;
MAYHYAAPSN SQILPAQEWN IVMEVMEPCK AVGNPTFGGC GRDYIHGIFP FGMFSNAVWD
LFFVENDMHK SHSSGYTEGV LNPEVVNIGA IFTFSTINGK VAKIAMKAAE QDVNSDPSIL
GGRKLAITLH DSNYSGFLSI VGALQFMESD TVAIIGPQSA VMAHPWTRPS RLSSFPYFIQ
TAPSDLFQMT AIADMVSYFE WREVIAVYSD DDQSRNGITT LGDKLAERQC KISYKAALPP
DPKATRDQVF NELVKVRMME SRVIVLHTLS KTGLLVFDVA KYLGMMESGY VWIASTWLST
ILDSTPLSSK TADSIQGVLT LRPHTPDSKK KREFSSRWNH LSNGTIGLNP YGLYAYDTVW
MITYALKTFF DQGGTISFSN ITSGTALVAG ELNLGALSIF DGGQQLLKNI LQINRTGLTG
PLRFGPDRSP VHPAYEVINV VGTGFRQLGY WSDYSGLSVA SPDTLYAKPP NRSRSNQQLY
DVLWPGEITK KPRGWVFPNN GRHLRIGVPN RVSYRDFVSK GKDTDDLHGY CIDVFTAAIA
LLPYAVPYKF VLFGDGLENP NYNQLVYKVA SNDFDAAVGD IAIVTNRTKA VDFTQPYIES
GLVVVAPVKK LNSSAWAFLK PFSPLMWGIT ASFFLIVGAV VWILEHRIND DFRGPPKKQI
VTMLWFSFST LFFSHRENTV SSLGRMVLII WLFVVLIINS SYTASLTSIL TVQQLSSSIK
GIETLITSND RIGFQVGSFA ENYLSDELDI PKSRLIPLGS PEEYATALEN GTVAAVVDER
PYIEVFLASH CKFSIVGPQF TRSGWGFAFX RDSSLTVDLS TAILTLSENG DLQRIHDKWL
KNKVCSDNSQ LGSDQLQFQS FWGLFLICGI ACFLALLVYF CMMVRQFSKQ FSEASPSSHG
SSRSARLQTF LSFVDNKAEV SKAKSKRKRG DMSLDSNGRE DKSRNGSTRT KQTDLPSXI
//
