ID   A5ARD1_VITVI            Unreviewed;      1243 AA.
AC   A5ARD1;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_035441 {ECO:0000313|EMBL:CAN69322.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN69322.1};
RN   [1] {ECO:0000313|EMBL:CAN69322.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM432907; CAN69322.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 3.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          642..806
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          909..948
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1160..1210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        916..930
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1191..1210
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1243 AA;  143306 MW;  6829A923D0A6B6A9 CRC64;
     MQDKLNESLA DFEEGLSXPP NVLATLQSWR MIEEILPLFN KPEGAAAEKE SPKLNLKPLP
     VELKYTYLEE NNQCPVVISS SLTSHQEKCL LEVLKRCKKA IGWQISDLKG ISPLVCTHHI
     YMEEEAKPIR QLQRRLNPHL QEVVLAEVLK LLQAGWRVCI DYRKLNVVTR KYHFPLPFID
     QVLERVSGHL FYCFLDGYSG YFQIEIDVED QENTTFTCPF GTYAYRRMPF GLCNAPATFQ
     RCTFEECLIN LEAVLHRCIE KDLVLNWEKC YFMVRQGIVL GHIISEKGIE VDKAKVELII
     KLPSPTTVKG VRQFLGHAGF YRRFIKGFSS LSKPLCELLA KDAKFMWDER CQNSFDQLKK
     FLTTTPIVRA PNWQLPFELM CDASDFSIGA VLGQREDGKP YVIYYASKTL NEAQRNYTTT
     EKELLAVVFA LGKFRAYLVG SFIIVFTDNS ALKYLLTKQD AKARLIRWIL LLQEFDLQIK
     DKKGVENVVA DHLSRLAIAH NSHTLSINDD FPEQSLMFLV KTPWYAHIAN YLVTGEIPSE
     WNAQDRKHFF AKIHAYYWEE SFIFKYCSDQ IIRKCVPKDE QQGILNHCHE NACGGHFASQ
     KIVMKVLQSG FTWPSLFKDA HIMCRSCDRC QRLGRLTKRN QMPMNPILIV ELFDVWGIDF
     MGPFPMSFSN SYILVGVDYV SKWVEAIPYK KNDHRVVLKF LKENIFSRFG VPKAIISDGG
     THFCNKPFET LLAKYGVKHK IATPYHPQTS GQVELANREI NNILMKVVNA SRKDWSIRLH
     DSLWAYRTTY NTILGMSPYR LVYGKACHLP VEVEYKAWWA IKKLNMDLIR AGAKSYETDF
     GTRVPLRSTG APISQLRIGY EATKHKNSQF RSQSSIPQGF SQLRNRFWHT SATSQHRSPH
     FEAAKWSAKI APVRGPTSEP PRPEAASPQA KPAPQKPQAK PASQNPLVRR YLTRARPFHS
     KLCFDTTTFQ LRSELADSFR LLRRYRMEHL LTPRDFFYPR VAMDFYQSMT TKQVRDPTLI
     HFTIDGRHGI LGARHIAEAL HILYEPSHFE DYRVWTSLSQ LEMHWTQRRG VLLEALFRIS
     EGYFFGPHHL IMATILYFEE KVHKKKLQRG DVIPLLFPRL LCQILEHLGY PSDPQLERKR
     ICREVFTLDK WTNMTTYRVE QPGRPQPAAR KAPPRHIPEG IPIASPTISR APPVTPASSE
     PSTSTDPRMT IPISEYRELC RSLQTLTTSQ SSLAQEMAAI RAC
//