ID   A5BCN2_VITVI            Unreviewed;      1287 AA.
AC   A5BCN2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_010638 {ECO:0000313|EMBL:CAN76716.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN76716.1};
RN   [1] {ECO:0000313|EMBL:CAN76716.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM454720; CAN76716.1; -; Genomic_DNA.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR005162; Retrotrans_gag_dom.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF13650; Asp_protease_2; 1.
DR   Pfam; PF03732; Retrotrans_gag; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
FT   DOMAIN          144..237
FT                   /note="Retrotransposon gag"
FT                   /evidence="ECO:0000259|Pfam:PF03732"
FT   DOMAIN          1033..1120
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
FT   DOMAIN          1183..1276
FT                   /note="Reverse transcriptase/retrotransposon-derived
FT                   protein RNase H-like"
FT                   /evidence="ECO:0000259|Pfam:PF17919"
FT   REGION          475..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1287 AA;  146609 MW;  B601C89439922236 CRC64;
     MAPLPGIEPR IKCGAIANAA ARDESNGAVA GELVKCDTPQ KGEFEVILNI MEAAPEDQHS
     HQGRQDNLNE FRSMRDRMHP PRMSAPSCIV PPTEQLVIRP YLVPLLPTFH GMESENPYAH
     IKEFEDVCNT FQEGGASIDL MRLKLFPFTL KDKAKIWLNS LRPRSIRSWT DLQAEFLKKF
     FPTHRTNGLK RQISNFSAKE NEKFYECWER YMEAINACPH HGFDTWLLVS YFYDGMSSSM
     KQLLETMCGG DFMSKNPEEA MDFLSYVADV SRGWDEPTKG EVGKMKSQLN AYNAKAGMYN
     LKEDDDMKAK LAAMTRRLEE LELKRMHEVQ AVAEAPVQVK LCPNCQSFEH LVEECPAISA
     EREMYRDQAN VVGQFRPNNN APYGNTYNSS WRNHPNFSWK ARATQYQQPD PPSQQSSSIE
     QIIANLSKVV GDFVGKQEAT NARVDQRMDR VIKEWIEWRV KDVKALITLR SGKKIEHPTP
     KPHVEKEEEM KKGKEMEDKG SEISEEKKDS DATIKAIPEK ELLKEEMLKK STSPPFPQAL
     HGKKGVRNAA EILEVLRQVK VNIPLLDMIK QVPTYAKFLK DLCTIKRGLT VNKKAFLTEQ
     VSAILQCKSP LKYKDPGSPT ISVMIGGKVV EKALLDLGAS VNLLPYSVYK QLGLGELKPT
     TITLSLADRS VKIPRGVIED VLVQVDNFYY PVDFVVLDTD PTVKEANLVP IILGRPFLAT
     SNAIINCRNG LMQLTFGNMT LDLNIFYMSK KQITPEEEEG PEELCIIDTL VEEHCNQHMQ
     XKLXESLXDI EEGFSESPIG LATLQSWRKI EGILPLFNEE EEAAVEEEIP KLNLKPLPVE
     VKYTYLEANN QCPVVISSSL TSHQENCLME VLRRCKKAIG WQISDLKGIS PLVCTHHIYM
     EEEAKPIRQF QRRLNPHLQE VVRAEVLKLL QAGIIYPISD SPWVSPTQVV PKKSGITVIQ
     NEKGEEITTR LTSGWRVCID YRKLNAVTRK DHFPLPFIDQ VLERVSGHPF YCFLDGYSGS
     GKDHLYMSIW KHLLYRRMPF GVMQCTWLHF QRCMLSIFSD MVERIMEVFM DDITVYGGTF
     EECLVNLEAV LHRCIEKDLV LNWEKCHFMV RQGIVLGHII SERGIEVDKA KVELIAKLPS
     PTTVKGVRQF LGHAGFYRRF IKGFSSLSKP LCELLAKDTK FIWDERCQHS FDQLKKFLTI
     TPIVRAPNWQ LPFELMCDAS DFAIGAVLGQ REDGKPYVIY YASKTLNEAQ RNYTTTEKEL
     LAVVFAMDKF RAYLVGLSSL SLLTIQP
//