ID   A5BIS3_VITVI            Unreviewed;      1323 AA.
AC   A5BIS3;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_018187 {ECO:0000313|EMBL:CAN83286.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN83286.1};
RN   [1] {ECO:0000313|EMBL:CAN83286.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM460891; CAN83286.1; -; Genomic_DNA.
DR   ExpressionAtlas; A5BIS3; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR013103; RVT_2.
DR   PANTHER; PTHR48202; ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR48202:SF1; ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   Pfam; PF07727; RVT_2; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          240..427
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          118..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1323 AA;  150671 MW;  FB69272AF1F2D5A3 CRC64;
     MVRSMSFSGK RKAKRKKKKI QLMYEEEEEE EESLNGHLAF TVSYLITATG TIYNLNIKST
     SEFLKSVEDH FKCANKSLAG TLMAKLTTMK YDEEVRLRQE GHNLALAVTH GVTKKKGKFR
     KGKKFPPKKS GSREGSQSHD GKFXGFLTTR KLKESEKFLY MGNRLKVEVV VVGTYRLLLD
     TVGFGILCDG LYKISLNHEF AQALITLHSN VGSKRGLINE NSSILWHRRL GHISRERIER
     LMNEGILQNL DFIDFQIFVD HSMFHVLQEK YFITFIDDLS RYGYVYLMHE KSQAIDIFEM
     FITEVERQLD KKIKIVRSNR GAEYYGKYDE SGQNPSPFAK FLEKHGIHAH YTMPSMPQQN
     DVAKRHNRTL MEMVRSMMSH SPVPISLWGE ALKTAIVRIV ETRNARFLEN GEISGSNEPR
     KVDIEEIRVD IPPPFLPQEI IAPQPIQQVE EHEQHNRDGS LPPENIAIEN VVEPPQLAPL
     RRSQRERRPA ISDDYVEGID YRDTFSPVSK KDSLKIIMAL VAHFDLELKQ MDVKTTFLNG
     NLDEDIYMEQ PEGFAKKGNE HLVCKLKKSI YGLKQASRQW YIKFNNTITS FGFKENTVDQ
     CIYLKXXGSK FIFLILYVDD ILLASSDLGL LRETKEHLSK NFXMVBMGEX NYVIGIEIFR
     BRSQGXLGLS QKGYIDRVLE RFNMQFMFIX CCTYIERNNM EREQTKKIPY ASAVGSLMYA
     QTCTRPDISF DVGMLGRYQS DPGLKHWKAA KKVMRYLQGT KDYMLTYKRS KQLEIAGYLD
     SDYGGCLDSL KRKWCLRDFA DTHEGLRNYF ATKSYSHRAA KLASTLRFSA SSLRHISGNF
     RRKSTTLYKK AAKFSQQKAD FATLCSDMLA MAVTPSFELR IVHRLKHWIL DFLSFEMHAR
     RSSLDVSDSL KGRSMLVAAI MDIVTSNCDS LEKVSFQPSL TGNAKMRDIA AAIEVIEDGS
     MHFDEPHVNA ESDDGGKGMR AQANLSSSVP GLWEDLRSQH VAVPFAAWAL ANWARASEHS
     RVASSPAQSR HLQQETKICS SSLSSRLQSP VNLYSKVGGA CVEKQRKFGK LSPHRVLICD
     GIVXMTTEIT DVEDAGTWRG NIEKIFIDIM AWYWGSSYCQ GQSRTRIVYK ANHILFSHTR
     PWILGHVFRA PSSFNKSGEL LHGGIPMTVA TISGGYHWHC LGLLPFKPSL MMLSTLLAII
     VMVASRATPF TFYILLYFTL LFLDRGNQLW FKPYVHSEEF ASCCSQSKRL CMIRSRNGNG
     AGSGRVALIP TPSRLFKTNL IPVPNPGRGG IRDEFQGRER GWEGFAEAIS SLWKLVQKGV
     EAI
//