ID   A5BP30_VITVI            Unreviewed;       952 AA.
AC   A5BP30;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAN74823.1};
GN   ORFNames=VITISV_034594 {ECO:0000313|EMBL:CAN74823.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN74823.1};
RN   [1] {ECO:0000313|EMBL:CAN74823.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM466192; CAN74823.1; -; Genomic_DNA.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR   PROSITE; PS50879; RNASE_H_1; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          46..225
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          450..579
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
SQ   SEQUENCE   952 AA;  108015 MW;  DB525B0266570040 CRC64;
     MKGIHPSIAS HKLNVFSTAR PVRQRIRRFH PERQRVIRNE IDKLLEAGFI REVSYPDWLA
     NVVVVPKKEG KWRVCVDYTN LNNACPKDSF PLPRIDQIVD STSGQRMLSF LDAFSGYHQI
     PMSPDDEEKT AFITPHDLYC YKVMPFGLKN AGATYQRLMT KIFKTLIGHS VEVYIDDIVV
     KSETREQHIL YLQEVFHLLR KYGMKLXPSK CAFGVSTGKF LGFMVSQRGI EVSPDQVKTV
     METPPPRNKK ELQRLTGKLV ALGRFIARLT DELRPFFLAI RKDGEHGWTD SCQNALERIK
     QCLMQPPILS SPIPKEKLYM YLAVSEWAIS AVLFRCPSPK EQKPIYYVSR ALADVETRYS
     KMELTALALR SAAQRLRPYF QAHPVIVLTD QPLRNILHKP DLTGRMLQWA IELSEFGIEF
     QPRLAMKGQV MADFVLEYSR RPSQQDESVK KEWWTLRVDG ASRSSGSXVG LLLQSPTGEH
     LEQAIRLGFS ASNNEAEYEA ILSGLDLALA LSVSKLRIFS DSQLVVKHVQ EEYEAKDARM
     AXYLAKVRNT LQQFTEWTIE KIKRADNRRA DALAGIAASX PIKEAILLPI HVQTDPSVXE
     XSTCNTIEAP QADGQEWMYD ITEYIRAGTL PGDXKQAHKI RVQAARFTLI GGHLYKRSFT
     GPYLRCLGHS EAQYVLAELH EGICGNHSGG RSLAHRAHSQ GYYWPTMKKD ATAYVKKCDK
     CQRYAPIPHM PSTTLKSISG PWPFAQWGMD IVGPLPATPX QKKFLLVATD YFSKWVEVEA
     YASIKDKDVT KFVEELPGVL WAYRTTPGRP TGNTPFALAY GMDAVIPTEI GLPTIRTDAV
     KQSDASMELG RNLDWTDEVR ESVAIRMXDY QQRASAHYNR KVRPRAFKNG TLVLRKVFEN
     TTEVGAGKFQ ANWEGPYIVS KASNNGAYRL QKLDGTPLLR PWNVSNLKQY YQ
//