ID   A5BPE6_VITVI            Unreviewed;       950 AA.
AC   A5BPE6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=VITISV_044177 {ECO:0000313|EMBL:CAN72567.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN72567.1};
RN   [1] {ECO:0000313|EMBL:CAN72567.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM466538; CAN72567.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PANTHER; PTHR42648:SF22; RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON TNT 1-94; 1.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   Pfam; PF00560; LRR_1; 4.
DR   Pfam; PF14223; Retrotran_gag_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          436..607
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          190..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          239..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        190..205
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..264
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  104812 MW;  6639E48D5508C994 CRC64;
     MSSQKFEVEK FNGSNDFTLW KLKMKALLVQ QKCAQAIEGE ETLPVGLTAV EKEEVVSRAH
     SAILLSLADE VLREVADETT AVGLWRKFES KYQKKSLTNR LYQKRQLHTL KMSEGMQVRD
     HLNNFNRIIL DLNGVGVKVE EEDQAMILLC SLPSSYENFV DTMMYGRBSI SXNDVKDALQ
     SKELQKLVSG SEEGSVETGL TVSRGRSMER NGGGRSKSXS KSKAAMRCFH XKEKGHFRKN
     CPQRQKGIGX GSNGNAQVVV AQKDSEKQDS SDEGEGGDVL TVSTSSSAES WILDTGASYH
     MAYSRDLFTT FKEWNGSVKL GDDGELGVKG SGSVQIKMYD GLVRTLNAWY VPGLRKNLIS
     VGTLDKNGYT FSGSGGVLRV SKGALVVMKG RLQHGIYTLM GSSVLGTAAV SSSMAIDSVE
     KKDNCTELWH RRLGHMSEKG LSILILEYIH SDLWGPSPVE SHSGCRYYVT FIDDFSRKVW
     VYFLKAKDEV FGKFKEWKTM VEKRTGKVVK TLRTDNGLEF CNKDFDEFCR KEGIVRHRTV
     RHTPQQNGVA ERMNQTLVQR ARCMRIDAGL SKKFWAEAVN TAAYLVNXSP STAIDFKTPQ
     EGSSSVCLVY GNGDVSSGLV GFTDSDHGGD LMKRRSLTCY IFTLFGCAIS WRASLQPTVA
     LSTTEAEYMS LTEGVKEGMW LNGFLGSLGL NLSKPVIYCD SQSALCLAKN LVYHERTKHI
     DVRLNFIRDV IEEKLFSIEK VATEVNPADM LTKPITTEKF KHSLDLGKIP SSLGKCQNLL
     FLDLSLNNLS GTIPPQVVSL SSLSISLDIS DNRLTGALPI EVGNLKNLGV LDVSNNMLSG
     GIPSSVGSCT SLEYLSMKGN FFQGSIPSSF SSLRGIRILD LSHNNLSGKI PEFLQDIHFQ
     LVNLSYNDFE GILPTEGVFK NVSATSIMGN SKLCGGIPEF QLPKXQLARA
//