ID A5BUI8_VITVI Unreviewed; 1958 AA.
AC A5BUI8;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=VITISV_017489 {ECO:0000313|EMBL:CAN63856.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN63856.1};
RN [1] {ECO:0000313|EMBL:CAN63856.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
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DR EMBL; AM471687; CAN63856.1; -; Genomic_DNA.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1766..1787
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1273..1447
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 276..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1580..1680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1847..1877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1591..1647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1664..1680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1855..1877
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1958 AA; 224551 MW; 592E7E312F09EBAB CRC64;
MHQLKISTHE GPHASASYEC TIMYSATYRA ASDPTTYCAT STYFSWDGPP RSIRSWTDLQ
AKFLKKFFPT HKTNSLKRQI SNFSAKENEK FYECWERYME VINTFPHYGF DTWLLVSYFY
DGMSSSMKQL LETMCGRDFM SKNPEEAMDF LSYVAEVSRG WDEPNAREVG RMNSQPNASN
AKVGMYTLNE GTDTKANFAA MARKRLEELE VKAISDTPMQ TKPCYICQSF ENLVEECPTM
PVVREMFGDQ ANFIEQFKPN NNAPYSNTYN SNWRNPPNFS WKPRAPQYMQ PGQAPPQASS
LEQAILNLNK VVGDFIADQK SINDQFMQVN AQIRQENAHI MQEMANRDRM MDGKSQKIDN
LQYQISRLTN LNTVQEKGKF PSQPHQNPKV IHEVEAQKGE SSLMREVKAV ITLRSGKEVD
LPTPKLEQEP DTKAEKEKME ENKERRKKAD LCTNKRGLNV SKKAFLTEQV SSIIQCKSPV
KYKYPGCPTI SMMIGETCVE KALLDLGASV NLLPYSVYKQ LGLGELKPTS ITLSLADRSV
KIPRGMIEDV LVQVDKFYYP VDFVVLDTNP IAKGTNYILI ILGRPFLATS NAIINYRNGV
MQLTFGNMTL ELNIFYMCNK QFHPGEEEGL EEVCMIDNLV EEHCDKKMLE DLNENFGDLD
EGLLEPLDLL ATLPPLKMKE EILPLFNKEE TQEAVKKEPP KLILKPLPTE LKYAYLEENK
QSPVVISSSL TTTQEDCLLE ILKRCKKAIG WKISDLKGIS PLVCTHHIYM EEEAKPVRQP
QQRLNPHMQE VVRAKVLKLL QAGIIYPISD SPWGEEVSTR LTSGWRVCID YRKLNVVTRK
NHFSLSFIDQ VLERVSSHPF YYFLDGYSRY FQIEIVVKDQ EKTTFTCPFG TYAYRRMPFD
LCNAPATFQR CMLSIFSDMV ERIMEVFMDD ITVYGSAFDE CLVNLEVVLN RCIEKDLVLN
WEKCHFMVPQ GIILGHIISS QGIEMDKAKF ELIVKLPSPT TVKGVRQFLG HAGFYRRFIK
DFSKLARPLC ELLVKDAEFI WDDRCQWSFE ELNDFAIGAV LGQKEDGKPY VIYYASKTLN
EAQRNYTTTK KELLVVVFAL XKFRTYLVGC KSEADQMDSL VQEFNLQIKD KKGVENVVAD
HLSRLAIAHN SHSLPINDDF PEESLMLIEV TPWYAHIANY LVTGEVPSEW KAQDKKHFFA
KIHAYYWEEP FLFKYCADQI IRRCVPEQEQ QGILSHCHES ACGGHFASQK TTMKVLSYDR
CQRLGKLTRK NMMPLNPILI VDLFYVWAID FMGPFPMSFG YSYILVGVDY VSKWVEAIPC
KRNDHRVVLK FLKENIFSRF GVLKAIISDG GTHFCNKSFE ILLAKYGVKH KVATPYHPQT
SGQVKTAYKT ILRMSPYCLV YSKACHLPFE VQYKAWWAIK TLNMDLNRAG VKRFLNLNEM
EELRNDAYIN SNISKQRLKR WHDQLVSRKQ FQKEQKVLLY DSKLHIFLGK LKSRWIGPFT
IHEVYSNGVI ELLTSTGTFK GKSKTKENRA LRKTKNSMRK ISHQLRTANS QCKKFRISFA
PPILNKKIFR ITTKKKKSNP HLVHISYGAQ QRGHTDPSAS REAQPSASTP QNPSQASQAL
TVPSSKGRVT SSPPQCQYST RRPPISSSPE PSVRRVPPKR ARTSGPRETS SQALANSQAL
EDIQRPSSIA REVIIKRPMV TVPPILGNLD SGPSGFIWIA PEVPSRVSDD FQRVFVPQNS
DGFLSVHDYS RRSDFHSHSF QHRRTLGIYM GFYFGPHHLI MVVFLYFEEK VHSKKLQRAD
AIPLLFPRLL YHILEHMGYP TKPHLKRRHH CREYFTLDQW TQLVERNSVE SAPETTPPKP
VPPVPAASTY PPATPPVPPA TSPPLLDFII ISGSEFRGMV LLFRTLNATH NALFWNMRDI
RAQQDRHSII LDQHTAILSQ IQQHLRLVPP QTDIPGPS
//
