ID A5C2Q7_VITVI Unreviewed; 2045 AA.
AC A5C2Q7;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=VITISV_005106 {ECO:0000313|EMBL:CAN75236.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN75236.1};
RN [1] {ECO:0000313|EMBL:CAN75236.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
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DR EMBL; AM480039; CAN75236.1; -; Genomic_DNA.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR028919; Viral_movement.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF01107; MP; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1858..1881
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1507..1676
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 313..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1677..1801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1948..1974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1988..2045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..810
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..862
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1730..1748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1776..1797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1958..1974
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2045 AA; 234216 MW; FFFFAC12D810170A CRC64;
MSRRSTDSQD TVVNSEKINY PKIQNDLDDW KLPKVSNQEI YKKRIFKFFT DYTIRTSEMS
VNLEQDDQVI RLLDSKSIDK HKKDGYNFMH FGMTQVAAKP LTRLGLNTSI FICLRDNRHL
NYRDSIIGAV QAGLNDGPVY FQFFPNFTVR LKDADILDSV VLHVKTHGFK FKPGNSPVSI
ITRKSNSEDV SSEDEWLSSL SFGVKKAGIN QKIKNNLFVP LRVHPHKRIN MVKGDISSKE
ETDELIKIFE EPQNQTVSKS INNLEAFKIR NYYPRPTFPY MQFEERNQYT QASYTSGTIY
KWNIDESESR IDLDNEDDIN QLDSSGEVSS QSSSDQKGCI KGNCNCXPKT INVISQDQEL
VLDILRKIKD EKTKQDLSEV FKKSVVKPKV KKIVNPYTLN EILNRFDQQS PKEISIKELH
DENLRKLMMM RQMLFWILLV GLSSRGAVKN CLQEGLVPIH LYEETSQSLF GANGKRLAIK
YKLTDVHIYN HDICINQTFI LVKDLNEKAL LGIPFLSSIY PICKEEDQRK KSIMKQFCMV
MRNLHMLCEI QRTAVARPIW STSWSLLSTY YISFRSLGSQ ESNSSNGVQF RAETKKLWLI
EGNCTKLKRN FALTFXDARI FTLAFPNAKI FAARFPNVKI CALTFSDVKI FAPPFSNAKI
QTNPEDVFLE DEWLDFLSLG RKRARTNNLK RQISNFSDKE NKKFYECWER YMEAINACPH
HGFDIWLLVV GDFVADQKSV NDQFMQEMAN RDRMMDGKQN DLSQKIDNLQ YQISRLTNLN
TVQEKGKFPS HHQNPKAIHE TREVKVVITL RSGKEVDLPT PKPEQEPEQE PETEAEKEKR
EENKGKKKGS NTKKEDVEAK VNEKSERTIN QEEVIKKHMP PPFLQALHGK RGINNASGIL
KVLRQVKCKS LVKYKDPGCP TISVMIGETC VEKALLDLEA SVNLLPYSVY KQLGLGELKP
TSITLSLADR SAYYPVDFVV LDTDPVAKGT NYIPIILGRP FLATSNAIIN CRNGVMQLTF
GNMTLELNIF YMCYKQFHPG EEEGLEEVCM IDNLVEEHCD KKMLEDLNEN FGDLDEGLLE
PLDLLANLPH LKTRKEILPL FNEEETPETI KEEPPKLILK PLPTELKYAY LEENKESPVE
CSLLEILKRC KNAIGWKISN LKGISPLVCT HHIYMEEEAK SVRQPQRRLN PYMQEVVRAE
VLKLLQVGII YPISDSPWVS PTQVVPKKSG IIVVQNDKGE EVFTSLTSGW RVCIDYRKLN
VVTRKDHFPL PFIDQVLERV SGHPFYCFLD GYSGYFQIEI AVEDQEKTTF TCPFGTYAYR
RMPFGLCNAP IKFQRCMLSI FSDMVERIME VFMDDITIYG SVFDECLVNL EVVLNRCIEK
DLRLIRWILL FQEFNLQIKD KKRLENVVAD HLSRLAITYN SHSLPINDDF PDESLMLIEV
APWYAHIANY LVTGEVPNEW KAQDKKHFFA KIHAYYWEEP FLFKYCADQI IRKCVPELGK
LTRKNMMPLN PILIVDLFYV WGIDFMGSFP MSFGYSYILV GVDYVSKWVK AIPCKRNDHR
VVLKFLKENI FSRFGVPKAI ISDGGTHFCN KPFEILLAKY GTSGQVELAN REIKKILMKV
VNTSRRDWSI RLHDSLWAYR IAYKTILGMS LYRLVYGKAC HLPVEVSPTD HFAQASSITK
SSLPPCEANS SPFHAPRPPR RRRAIHLSSI SAMVRTRGGH IDPSASHEAR PNASVPQDPS
QASQALTVPS YEGKRPPISP PPEPSVHRXP PKRARTSSPG ETSSQAPSNS QAPEDTQRPS
GIALEVIIKR PMLEDQEQFR QWTSTSQRNM VRILSRGTSG DTCLLRKELP SEMLLVDVLL
RIFMGFYFGA HHLIMATLLY FEEKVHKKKL QRADTIPLLF SRLLCHILEH MGYPTEPHLE
LRHHCREHFT LDQWTQLVER NSAKSAPEAA LPRLAASTDP PALPPIPPVV PPPSQDFITI
SGSEFCGMQH LSLPPPQTDI LGPSEPRDLV EDTILAEETI TTDVPPQATH ETALEPSRPP
ENPAP
//
