ID   A5CBM6_VITVI            Unreviewed;      1429 AA.
AC   A5CBM6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VITISV_030041 {ECO:0000313|EMBL:CAN64418.1};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN64418.1};
RN   [1] {ECO:0000313|EMBL:CAN64418.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT   vinifera L.): coping with a highly heterozygous genome.";
RL   PLoS ONE 2:e1326-e1326(2007).
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DR   EMBL; AM489204; CAN64418.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR013103; RVT_2.
DR   InterPro; IPR004242; Transposase_21.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PANTHER; PTHR42648:SF24; RETROTRANSPOSON, UNCLASSIFIED-LIKE PROTEIN; 1.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF07727; RVT_2; 2.
DR   Pfam; PF02992; Transposase_21; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT   DOMAIN          152..168
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50158"
FT   DOMAIN          375..539
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          638..702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        647..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..689
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1429 AA;  162124 MW;  4BF4A3CF332B4C70 CRC64;
     MATSSSDSFP IAINATQQIT ARLTPTNFPS WHAQFESLLL SYNLFGYVDG THTCPPLPXI
     TKYLHSVKTI ADELALIDAP LSQDDISLYV LHGLRSDFRD IVAPIRARES SLSFEELHDL
     LLGHEAYLRR LDSTSQSLIK SRQLKQYKYP PRCQYCDQQG HIAKYCPKLX PSEATVNCTT
     TTSSPDKRWL IDSMASHNIT SQVSNLQFHS EYDGTDEVII GDGSGLPITH SGSLTLSFPN
     RKFQVEDTLC VPTINKNLIS VHHYTKQNNV ILEFHPTYFL AKDWRTGEIL LQGPCENGVY
     PLASSPAATP IAFVHERTSA XGWHXRLGHR SFKVVXRLIS SFSLPTTSCL SGSNNCHSCS
     XNKAHQLPFH KHGLTSTTPF DLLYTDVWGP SPTPSLNGHR YYVIFVDHFT KYGWFFPLHQ
     KSDVKTIFPH FYKMIETRFN IKIKGVYSDN GGEFTVLRPF FTTHGISHYT TAPYTPQQNG
     VSERRHLHIV ETGQTLLSHA SLPSEYXAYA FATATYLINR LPSPVLHHIS PLQALFKQQP
     RYEKLRSFGC LCFPLMKPYN TNKFQKKSVP CIFVGYSTSQ SAYLCXHLQS QRIYTSKHVT
     FDESVYPFKQ VSMQSPTDSS PSETSSFSGP ILQLASRELP XITRAQGDIP SASSTPSEDP
     ALVQPQEAPL STLDQVTLRP STSVSQPENS MPSSPPPCPR TIITRSMNNI FRPKQLHTTT
     KHPLPEPPEP SCNLVGCKFV FRKKRNPDGT ISRYKARLVA KGFHQRPGID YSQTFSPVVK
     PWYKALRDAL LSFGFIHSAT DNSLFIYKSH DILCYCLVYV DDIIVTSNTL SFVNNIINKL
     GSTFLVKDMG SLHYFLGIEV IPMPQGLFLS QHQYIWDLLS RTSMENAKET LTPMSTTAKL
     TVQDNFECVD STEYRKIIGA LQYLGLTRPD IAFAVNRLSQ FIDVKWALNT DTRVSTTTFI
     TFIGPNPISW SARKQMAVSR SSIEAEFRAL ATATSETVWL HSLIKELGLT LREAPQMFCD
     NIGANHFSLN PXQHRRMKHI EIDLLFVRDL VKKGTIRVQH IHTIDQLANL LTKSLSXQRF
     QLLRSKIGVA DGTSILRGHI RTASLNNKQV IVKEVIESNI CSLMESILVI EYGIGMEKMD
     PVEDFQMSHN NIMTNANAEK PLYLGCMKYT KLSALVKLYD LKACYGWFDK GFSKLLQLLG
     DMLPLNNEMS LSINQYKDAI ACLTCGKSRW KINNEGKKIK KGLPSKVLWY FPPIPRFKRM
     FQSSKTAKHL MWHAKDKEYD GPRQPGKNID VYLSPLVDDL KTLWEKKVKT YDAHLLEVFT
     LKVIILWTIS YFPTYENLAN CTVKGYYACP ICGEGTYSQR LKYGRKNLYM GHRRFLPRNH
     PYWRQKKALN GEQDFRIPPK ILSGEEILEK VDLIPISWGK MKIKSLELM
//