ID A5DA03_PICGU Unreviewed; 465 AA.
AC A5DA03;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=Pre-mRNA processing factor 4 (PRP4)-like domain-containing protein {ECO:0000259|SMART:SM00500};
GN ORFNames=PGUG_00108 {ECO:0000313|EMBL:EDK36010.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK36010.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK36010.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408155; EDK36010.2; -; Genomic_DNA.
DR RefSeq; XP_001486731.1; XM_001486681.1.
DR AlphaFoldDB; A5DA03; -.
DR STRING; 294746.A5DA03; -.
DR GeneID; 5128863; -.
DR KEGG; pgu:PGUG_00108; -.
DR VEuPathDB; FungiDB:PGUG_00108; -.
DR eggNOG; KOG0272; Eukaryota.
DR HOGENOM; CLU_000288_57_20_1; -.
DR InParanoid; A5DA03; -.
DR OMA; LNEPICY; -.
DR OrthoDB; 5476798at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19846:SF0; SFM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08799; PRP4; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00500; SFM; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF158230; PRP4-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 27..82
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
FT REPEAT 187..227
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 232..273
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 274..315
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 316..357
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 430..465
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 51685 MW; A5882333AA6D7D4D CRC64;
MDLKDVPVAN EPKTNKTNLA EVQGVPEDDE EVKRLLRKLG EPVTNYGEGP GRRRERLKNV
LEMRSKSEPD EMSEEEDDDN EVFYTPGPES LLICRKNILH DSLKRASQRI KAQSEATKDP
IKLLKHRRNI NSRLKTFELL GSQVVPGVTR TISSIRASPY GGILACGSWD GTVSILNQED
LKTKIQRTGH SEKVGSIDWG PENTFVSGGQ EGNINQWKLD LSDDTMEAAT IERAHGERIT
STLYHPTFDY IASTSFDQTW KLWDANTHEE LLVQEGHSKS VLCGAFQPDG SIFCSGSQDA
MARLWDLRSG RCISTLQGHA QAIHSIDFSP NGYHMATASA DCSVKVWDLR KITPNNSNEI
FTIPAHTKLV SCVRFFHGTR FPGALSQEVT DENDNAGEIL DSSGSYLVTS SYDGLVNVWS
ADNWIKVCSL RGHTDKVMSC DVNGDGSSIY SCGWDKNIRV WGSID
//
