ID A5DLJ9_PICGU Unreviewed; 653 AA.
AC A5DLJ9;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=PGUG_04150 {ECO:0000313|EMBL:EDK40052.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK40052.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK40052.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408159; EDK40052.2; -; Genomic_DNA.
DR RefSeq; XP_001483421.1; XM_001483371.1.
DR AlphaFoldDB; A5DLJ9; -.
DR STRING; 294746.A5DLJ9; -.
DR GeneID; 5125338; -.
DR KEGG; pgu:PGUG_04150; -.
DR VEuPathDB; FungiDB:PGUG_04150; -.
DR eggNOG; ENOG502QTER; Eukaryota.
DR HOGENOM; CLU_014123_0_0_1; -.
DR InParanoid; A5DLJ9; -.
DR OMA; YQKCIKY; -.
DR OrthoDB; 1387259at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR PANTHER; PTHR35859:SF1; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..461
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 572..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 74702 MW; 7B4CCBAD3DAD4B99 CRC64;
MTTTADLEDR VIDDIGPMAF SDKYCPNAQQ TFRICLNLKK LIDRVIAVEY KEEEITSSNS
PVINDKVLKL AYKAAGGKGN GKPGTSSIKY QASLVFCLLR VCDWYWQQAE YELTDNYLYT
LRAIAAQKLA VMIIDGTRND EVLFLGMLCH RYTIALNGVD AHPVSALELA VDMHSTIVMG
SSGYQRCIRW LWRGWIIQSS IDPHSYVLYK GVNSLSIRSH FDPARVRTPL YQNILEVGFS
FIYLLLYTII LNTNQQETKP LDPFEVFFYL FTVGSILDEV IKLYHIGFNY IRFWNVFNDS
MYAIISVAIG FRLLSLNNTG HLRDRYDEMS FRILSCAAPF MWSRLLLFLD AQKFVGAMIV
VLKVMMKESL IFFVMLGVVI LGFLQGFLGL DASDGKSEAT RRILISLVKS VIGEASFDDV
APLVPPYASI MYYIYSFLLT VILMNILIAL YSTSYASIVE NSTSEYFGLV AQKTLKYIRA
PDEDLFVPPL NLIEVLLLPF SFVMSYNSYK ALNYYVMLVI YSPLLCYITS VEISNAKRIQ
YNRYKGLPDD ANEYDADWDL TDGFDDDVST NWAGMREQDD GTRRRLQEQH AGEQQDPEFA
INQHEFEDDI ECAVQPVERA KDAGVKWELF VLYAKVDELT KMVNELVQEK REK
//
