ID A5DVA0_LODEL Unreviewed; 847 AA.
AC A5DVA0;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=UNC-45/Cro1/She4 central domain-containing protein {ECO:0000259|Pfam:PF11701};
GN ORFNames=LELG_01286 {ECO:0000313|EMBL:EDK43108.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK43108.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK43108.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981524; EDK43108.1; -; Genomic_DNA.
DR RefSeq; XP_001528766.1; XM_001528716.1.
DR AlphaFoldDB; A5DVA0; -.
DR STRING; 379508.A5DVA0; -.
DR GeneID; 5235693; -.
DR KEGG; lel:LELG_01286; -.
DR VEuPathDB; FungiDB:LELG_01286; -.
DR eggNOG; KOG4151; Eukaryota.
DR HOGENOM; CLU_357916_0_0_1; -.
DR InParanoid; A5DVA0; -.
DR OMA; VLIKTWS; -.
DR OrthoDB; 2047697at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024660; UCS_central_dom.
DR PANTHER; PTHR45994; FI21225P1; 1.
DR PANTHER; PTHR45994:SF1; FI21225P1; 1.
DR Pfam; PF11701; UNC45-central; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT DOMAIN 147..324
FT /note="UNC-45/Cro1/She4 central"
FT /evidence="ECO:0000259|Pfam:PF11701"
FT REGION 198..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 95447 MW; 1AE287D6062959ED CRC64;
MAGVNEKENL NTVRGDLEKL YDEALSLTLT LALPQTILSS QSLKEIKDVL LNATQKSSDS
GFLYTKLTTE PERFLQLAKN LDDTTILLTI VELKKPIITT PDIQKILSAL RIKIKDGEKE
ESLANCKFYL QLYASLITQT KIVNTQHIGL FLTLVGKIAK VDHLVLIIVV QCLQIEKANT
IEAIKDYLEV QIGDEADDVG RTSGDSDSGS GSGGGNIKNN DDDENIPYID GASFKNFLAV
VEMCFPVIPE ETTQIYTRKR TKEYFLEKKH EKTFYIPILK CMSASCIVEN CRKFNADNYK
NLMENSFQSY DKPVKVLASL VLAKEWSFIH QLLNNKKIKI TDVADCLMLY IEGESENDKD
HENYIDFAVE GLTYVSLFWE AREWMRVDVS FVEKLLDIFQ RSSKSTNINT SIQYVVLTIL
ANLTRSKSRT SSQYQGSRSE LKQAVMPKVG SDSNEEKIDG IRLFNEELLK DDELISKLSL
VKTYESSSKN IMNAVVDIIY NISSDQKKSV RTELVKQGAL TIIVNYLIKN SKIEKVEKRL
LPTIPNDAQQ AEIYLKALQS LARMMISVNP EIAFKNYDVK TTIPFLTQLL GNNENINDND
SNNDNDNNDN DNNDNNNNNN NLELTLLDKY ESLLALTNVA SIENPSLRDF IITEFFPYVD
DLILSSHLQL ATFQLLSNLI NRPVLLAKFF NVEQTKNKER LLITLKLFNS VEVNLQVAVG
KFLVNATEFD MIAEVLVSTV TIRNELLEIL VSILDRQLGH SGDENKSNIS SHNNNSASGD
QEQKELIIVA SYLLVNLVYA AANKDLSILA AIRDYKGLKG ACKEILTRGS PEAKEAMHSV
VEVLEFK
//
