ID A5H6I0_PETMA Unreviewed; 222 AA.
AC A5H6I0;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Variable lymphocyte receptor A diversity region {ECO:0000313|EMBL:ABO21125.1};
DE Flags: Fragment;
GN Name=VLRA {ECO:0000313|EMBL:ABO21125.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|EMBL:ABO21125.1};
RN [1] {ECO:0000313|EMBL:ABO21125.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PmVLRA.1A05 {ECO:0000313|EMBL:ABO21125.1};
RX PubMed=17468760; DOI=10.1038/ni1463;
RA Rogozin I.B., Iyer L.M., Liang L., Glazko G.V., Liston V.G., Pavlov Y.I.,
RA Aravind L., Pancer Z.;
RT "Evolution and diversification of lamprey antigen receptors: evidence for
RT involvement of an AID-APOBEC family cytosine deaminase.";
RL Nat. Immunol. 8:647-656(2007).
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. AMIGO family.
CC {ECO:0000256|ARBA:ARBA00005670}.
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DR EMBL; EF094633; ABO21125.1; -; mRNA.
DR AlphaFoldDB; A5H6I0; -.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR031283; AMIGO.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24368; AMPHOTERIN-INDUCED PROTEIN; 1.
DR PANTHER; PTHR24368:SF210; SURFACE ANTIGEN BSPA-LIKE; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00364; LRR_BAC; 3.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:ABO21125.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 7..32
FT /note="LRRNT"
FT /evidence="ECO:0000259|Pfam:PF01462"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABO21125.1"
FT NON_TER 222
FT /evidence="ECO:0000313|EMBL:ABO21125.1"
SQ SEQUENCE 222 AA; 24983 MW; 31CB31F04CB44AD8 CRC64;
TCETVTGCTC NEGKKEVNCQ YKGLKAVPSE IPADTKSLDL KYNAFNKLPS DAFKGLTALT
WLSVSNNELK SLPAGLFDQL VELKQLYLSR NQLKSLPSGV FDSLTKLTIL QLDYNQLQSI
PEKVFDKLTQ LQQLYLLNNQ LQSVPYGAFD RLRSLKDIFL RTNAWDCSRC EILYLSSWIR
ENSNKVKDGT GQNLHESPDG VTCSDGKVVR TVTNETLKYE CP
//
