ID   A5IL98_THEP1            Unreviewed;       814 AA.
AC   A5IL98;
DT   26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Alpha amylase, catalytic region {ECO:0000313|EMBL:ABQ46971.1};
GN   OrderedLocusNames=Tpet_0953 {ECO:0000313|EMBL:ABQ46971.1};
OS   Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 /
OS   RKU-1).
OC   Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC   Thermotoga.
OX   NCBI_TaxID=390874 {ECO:0000313|EMBL:ABQ46971.1, ECO:0000313|Proteomes:UP000006558};
RN   [1] {ECO:0000313|Proteomes:UP000006558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1
RC   {ECO:0000313|Proteomes:UP000006558};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C.,
RA   Tapia R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.;
RT   "Complete sequence of Thermotoga petrophila RKU-1.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABQ46971.1, ECO:0000313|Proteomes:UP000006558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1
RC   {ECO:0000313|Proteomes:UP000006558};
RX   PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA   Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA   DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA   Noll K.M.;
RT   "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT   the Thermotogales.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; CP000702; ABQ46971.1; -; Genomic_DNA.
DR   RefSeq; WP_011943514.1; NC_009486.1.
DR   AlphaFoldDB; A5IL98; -.
DR   STRING; 390874.Tpet_0953; -.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   KEGG; tpt:Tpet_0953; -.
DR   eggNOG; COG0366; Bacteria.
DR   eggNOG; COG4945; Bacteria.
DR   HOGENOM; CLU_010079_0_0_0; -.
DR   Proteomes; UP000006558; Chromosome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.1190; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR019248; Glucodextran_C.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10357:SF215; ALPHA-AMYLASE 1; 1.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   Pfam; PF09985; Glucodextran_C; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49344; CBD9-like; 1.
PE   4: Predicted;
FT   DOMAIN          28..422
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   814 AA;  93913 MW;  1B5E67101BBEFC44 CRC64;
     MGRSFFTFLL ILAVSLFAVS WRDVVLYEIM IDRFNDGDPT NNDQGYGEYD PSDPAKYSGG
     DLKGIIDKLD YIRGLGVDGI WITPPVANQW WDPWVNYGGY HGYWARNFKE VDEHFGNIET
     YRKLSEEIHR KNMFLIQDIV VNHVGNYFRF KAGKFEINTG SVPTFAPTQF PFNMNDYNDP
     KQREMNVYHW TPDITNYNDI HQKLNYQLSG LDDLNTENPM VRSALKDSYG FWIKEVGVDG
     FRVDTAMYVP KDFWDDFFFG KDGIMTLKDD FIAFGEAWLT SPPMDDSAEK EIESYFDHGF
     NAMLDFPLCE EIRRVLKGGK PTSWLAYRIE RRNQTLEKGL LVTFIDNHDM ERFSRGTDEK
     TLRMAVAFLM TLPGIPVIYY GTEQSFEETR ASMFAKGWGS GGKDHFEKGE MYDFIKSAVE
     FRKSHTATRY GKVKVLLSNS EGAGLLVYEV KDENETLIVV LNTSNNDKIR TIDGVFPSME
     KVFSSDREAR VVVQEKSTVF IVPPKSLTVF KLSSVNKYEK QTTNLTLKTT VNIYEDRVVI
     SGETNGKRMY AYIDGLYQTI PEKVNIVDGK YSLSLDLYKM GPGNHFIILK VYGSNPKEVL
     YSEEIWFEVS IPTEKLAEVT DPMNDDHGPF GRYKYPLDLT FKRQMDLIGA KVERMGPNLI
     VWIKTREITT SWNPPLGFDH VSFQIFLDDP RRKGAEALPF QNYAIDDWDY EIFITGWNVA
     IFSSEGATEK KFGVQIGSPE VVVVDGWIKI AVKGEWIDFP ESFNGWKLYL TTWDYDGVEN
     RFRPLEEEPK AYRFGGGNNT EPYIMDDLWI EIKE
//