ID A5K5A3_PLAVS Unreviewed; 359 AA.
AC A5K5A3;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Ubiquitin activating enzyme, putative {ECO:0000313|EMBL:EDL45831.1};
GN ORFNames=PVX_092830 {ECO:0000313|EMBL:EDL45831.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45831.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45831.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45831.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45831.1}.
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DR EMBL; AAKM01000005; EDL45831.1; -; Genomic_DNA.
DR RefSeq; XP_001615558.1; XM_001615508.1.
DR AlphaFoldDB; A5K5A3; -.
DR STRING; 126793.A5K5A3; -.
DR EnsemblProtists; EDL45831; EDL45831; PVX_092830.
DR GeneID; 5474854; -.
DR KEGG; pvx:PVX_092830; -.
DR VEuPathDB; PlasmoDB:PVX_092830; -.
DR InParanoid; A5K5A3; -.
DR OMA; EFFGQFD; -.
DR PhylomeDB; A5K5A3; -.
DR Proteomes; UP000008333; Chromosome 9.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF29; NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 13..348
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT REGION 208..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 40875 MW; 832284D561EA6E41 CRC64;
MKNNEEWEKE KIYDRQLRLW GVKAQNRMMK SNVLILGLSG INIEICKNLI LNGINITIID
DNIVDEEMVE NIFFLNESDI QNYACVAIFK ELKSINKMIN MKAYIGRMDT SNDSIIIESE
LVQNADGEIS NTKMGKTFSV EKYISNYTSV CVSCEDYPLY KLVKMNEFCH EKNIGFFAAM
CNGKFAFLFS DFGNHVIEES YYKAKEGQRK GETGANKAGE LQKEGETGAN NGGIPIQYCT
LSHFLKVPFE NFDKKTNKII FPMFALILFE LNKQLNKSDK SIDEQEFSTF CDQFSLAKCK
ESLGEITKTY RVAFSPSCSI MGGVTSQEIR KFVSKQHESI PNFCVFDMNQ SVVCTSMIS
//
