ID A5K9R5_PLAVS Unreviewed; 1542 AA.
AC A5K9R5;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 03-MAY-2023, entry version 62.
DE SubName: Full=Bromodomain protein, putative {ECO:0000313|EMBL:EDL43803.1};
GN ORFNames=PVX_081275 {ECO:0000313|EMBL:EDL43803.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL43803.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL43803.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL43803.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL43803.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAKM01000013; EDL43803.1; -; Genomic_DNA.
DR RefSeq; XP_001613530.1; XM_001613480.1.
DR STRING; 126793.A5K9R5; -.
DR EnsemblProtists; EDL43803; EDL43803; PVX_081275.
DR GeneID; 5472800; -.
DR KEGG; pvx:PVX_081275; -.
DR InParanoid; A5K9R5; -.
DR OMA; NVFLADC; -.
DR Proteomes; UP000008333; Chromosome 2.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR PANTHER; PTHR15398; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR15398:SF4; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 828..904
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1064..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1274..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1327..1378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..285
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..709
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..964
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1091
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1098..1132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1378
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1542 AA; 167415 MW; D0DA6A3A5615EA05 CRC64;
METRRSLRIR GDPPKEGPRG GNKSTAKEEP KTKGGGKAKG DAKKGAGGGK AKEEKGKKTS
QGDQNKKEVK GPAGGKRVKG EVEGGEREEG TEQDISNETN EAEELPKKGS KTGKDASNRV
EATKGKKSLE ETNPITTVDA ESECTDVTSL SNKRSERNVK GGGMLLRKQS SGTIENDGGN
GSTSRSRKGK EITGGTSGGG IKGVKEEEGG EEDHSLRRGK SKEGSKQNDS VKREDQGGGC
GRSRKGGSAK GKAAGKGSPG KAPPGKVPPG KVPPGKDPPD KGPPGKGSPG KGSPGKGSPG
KGSSGKGSPG KGSTGGGSPG KGSPDVGSPG DQRKGASQTK RAKGAALPIK VKVKGDASVG
KGGGKGGGKT AGKTSDPAAD TAADAANEKI PQTVPPTSEN ASPQGKGKWR GKGNRRGGAE
DEPVPASHFI KNMDSEELES SRARCSSNRS STVEWSEQLD AGVSAIGGAK QGGAKPTINR
SIKRRLSQIL DVMKKKQVFQ LIGDQDEQYG IHFGGDESGG ATTPPGGDLT RGATTEKGKE
PTDAKAEQIR NWPFLQRVNL DVIYNKLHFD FYEGEEDFHR DMLIIFDRIK LAIETEQNPK
EKQNLYQLRC STWKTYEGEF YKLLLSMKGT KEAKKFSSAQ KELREQEDKS LAQLLLGGKR
SEEQLEGKQL EEKQLEEQPL KEQRLGEAHP AGDRADHDHD HDHAHVRRSS SSVSVEASSP
LGGKKPAEGS HTPFRVRLRL GSFSLDEGAA AGKGGEDNRS GVASLRVSGA TSPEKGIAGG
EASVAAGVAA GVEASVDADV AANAAAAEAP TEEWKRLIRD HVLQSLTRDS STAFYFTTPV
LEDKNLNEHI KSEYKRKIKK PMDYTTVSRN LTQGVYQNPS EFYRDLKLIF QNCFEFNPDT
LQNQYIIEAA KRGQERSSNL WRKWKGRILQ AYERGGKAAG EPSQAVKEPP TAPTASTTPT
APTTPLNPAS YAEFFKGMAK KKKKFSSIYS LWVEYLLANR VSFEQLCHMR GINWRALNEK
SQAKVSSPRE VNLHRFKKLN KRSLPFYVFR EEYQAALRER RQEGGKLEQL AEEEKPSEEE
KQSEKPAEVG GDSPARDNPQ DESSKTLLKD PRTWSHQQKG KPREGRAPKE PSLKPFRRRK
RRINDSIFFD EDVFESYLEG KRSCVVKCAR NVFLADCFYY RSVVQSLGDF MAEGGDERGE
ETKEGDLSGM IPKEERIGGV TPKEEDLSGV TPKGEDLSGG NAEEAPPKAS KIAFRVRAGG
GKKQAQRAVC KGFEESPWGG DETDASWGGG GGGAHEGSVM EGGITHKGNE HTGVESLIEK
CPAEGCQTEE RAAEETDGEP PLHGIGQLAN NAAGPPQGIK EKRKKKKKKG EKSHRAVVRR
QVSRPLRRNT LVMNLQMGYC PLEDSSFFQV NEGHVYRQHI DFGFSFVFRS REKLDVALKM
ERRNVPLFEE DCLQLITIDV MNKCKRNDHL KFLLCNRMAG TGRSLVQVLS DYFARLNSPA
GLHEAASELS RILPRDVDVL MRLEKDDVTH VTTIAILKRK VL
//
