ID A5KAB5_PLAVS Unreviewed; 1089 AA.
AC A5KAB5;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Cell division cycle ATPase, putative {ECO:0000313|EMBL:EDL43751.1};
GN ORFNames=PVX_088085 {ECO:0000313|EMBL:EDL43751.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL43751.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL43751.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL43751.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL43751.1}.
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DR EMBL; AAKM01000014; EDL43751.1; -; Genomic_DNA.
DR RefSeq; XP_001613478.1; XM_001613428.1.
DR AlphaFoldDB; A5KAB5; -.
DR STRING; 126793.A5KAB5; -.
DR EnsemblProtists; EDL43751; EDL43751; PVX_088085.
DR GeneID; 5472742; -.
DR KEGG; pvx:PVX_088085; -.
DR VEuPathDB; PlasmoDB:PVX_088085; -.
DR InParanoid; A5KAB5; -.
DR OMA; CIKEHVH; -.
DR PhylomeDB; A5KAB5; -.
DR Proteomes; UP000008333; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.10.330.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR029067; CDC48_domain_2-like_sf.
DR InterPro; IPR003338; CDC4_N-term_subdom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23077; AAA-FAMILY ATPASE; 1.
DR PANTHER; PTHR23077:SF171; ATPASE FAMILY PROTEIN 2 HOMOLOG; 1.
DR Pfam; PF00004; AAA; 2.
DR Pfam; PF17862; AAA_lid_3; 2.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01073; CDC48_N; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF54585; Cdc48 domain 2-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 2.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:EDL43751.1};
KW Cell division {ECO:0000313|EMBL:EDL43751.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 272..356
FT /note="CDC48 N-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01073"
FT DOMAIN 509..645
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 829..966
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 107..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1024..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1040
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1089 AA; 121752 MW; 5E81F7305790FDFD CRC64;
MKGEKMQPPY PPRKARVPCF LVVALVLPLI VQLSHQIGLK KDVRFTLGSG SHQSRFPFAK
RKNLGNSLFL PLGRKRNTLT SIGTDLFKER DSPGGVKDEW KSRVVNEEAS KNGGHHPAVG
IPIDGKSDRK EKHLGGDARL GGNVPTGETN LGITPSEEQT HIVQNNLVSG LISRFWPFGE
KKERGSGREE TPKGSANGGG GGDPPEPEKH PWWGNTPKES ASVDTPPGEA SSEAPPEGGP
PRERRRPSRG SDQDKETNFL LKALETGKFP SYCLVENVDE QIDNCEIYLS KAKMEELNLS
EGFTVLLKGK KKKEMLAIAK LDRRLQKHFV VISFAMKKNL RLMHNDIIKI FPLMKVHPLR
TVVLSPFSDT VGGLSKAELE QEVLRPYLKG TFKPLCEGTN VYIPHKGRKV EFRVVKLVKE
GEEAARKEEQ PLRESRADVP TSQHYGYVGD NAIITLDEEY LNREDYEEHT DDITYEDLGG
MKKQLNKIRE LIELPLKYPE IFISIGISAP KGVLMHGIPG TGKTSIAKAI ANESNAYCYI
INGPEIMSKH IGESEQKLRK IFKKASEKTP CIIFIDEIDS IANKRSKSTN ELEKRVVSQL
LTLMDGLKKN NNVLVLAATN RPNSIDPALR RFGRFDREIE IPVPDEQGRY EILLTKTKKM
KLDADVNLRK IAKECHGYVG ADLAQLCFEA AIQCIKEHVH FLDLDEEDFI AFMELSVEGE
RLSGDEGRRS GTRPLLSDTR PPVTASSPPP RGAKKIPPYI LNKLTIKAKH FQHALNICNP
SSLRERQVQI PTVTWEDIGG MQDVKEQLKE TILYPLEYKH LYAKFNSNYN KGILLYGPPG
CGKTLLAKAI ANECNANFIS VKGPELLTMW FGESEANVRD LFDKARAASP CIIFFDEIDS
LAKERNSNNN NDASDRVINQ ILTEIDGINE KKTIFIIAAT NRPDILDKAL TRPGRLDKLI
YISLPDYKSR CSIFKAILKN TPLSADVNLH EMAKRTEGFS GADITNLCQS AVNEAIKETI
RLVSQRKGGP EKRSGAKANG GADDHYDPVP TLAKKHFDLA FKNARISIRP EDVLKYERFK
EKLSLQSFD
//
