ID   A5KPN0_9FIRM            Unreviewed;       395 AA.
AC   A5KPN0;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   SubName: Full=Putative permease {ECO:0000313|EMBL:EDK23706.1};
GN   ORFNames=RUMTOR_02214 {ECO:0000313|EMBL:EDK23706.1};
OS   [Ruminococcus] torques ATCC 27756.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Mediterraneibacter.
OX   NCBI_TaxID=411460 {ECO:0000313|EMBL:EDK23706.1, ECO:0000313|Proteomes:UP000003577};
RN   [1] {ECO:0000313|EMBL:EDK23706.1, ECO:0000313|Proteomes:UP000003577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27756 {ECO:0000313|EMBL:EDK23706.1,
RC   ECO:0000313|Proteomes:UP000003577};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDK23706.1, ECO:0000313|Proteomes:UP000003577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27756 {ECO:0000313|EMBL:EDK23706.1,
RC   ECO:0000313|Proteomes:UP000003577};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Ruminococcus torques (ATCC 27756).";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDK23706.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAVP02000012; EDK23706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5KPN0; -.
DR   PaxDb; 411460-RUMTOR_02214; -.
DR   HOGENOM; CLU_017959_1_2_9; -.
DR   Proteomes; UP000003577; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        306..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        364..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   395 AA;  41729 MW;  59C7BC24B7A8CFF6 CRC64;
     MFAMFGASVL VPFVFGLNPA VVLFMNGIGT LLFILITKGK APAYLGSSFA FLAPAGIVIE
     KWGYSYALGG FVAVGFLGCV LALIIRKFGS KWIDVVLPPA AMGPVVALIG LELAGTAASN
     AGLTASSIDP KNVIVFLVTL LTAVLGSVLF RKFFAVIPIL IAIIAGYIAA LLCGIVDFSK
     VASASFFALP NFSTPKFKWE AIVIILPVIL VIASEHIGHQ IVTSKIVGRD LLKDPGLHRS
     LFADNFSTMI SGFIGSVPTT TYGENIGVMA MTKVYSVYVI AGAAVLSIIC SFIGKMTTLI
     STIPGPVIGG ISFLLYGMIG TSGIRILVDS QVDYARSRNM AMTSIIFVTG LSGIKVQFGS
     IQLTGMVLAC VVGMIMGLMF FLFDKLKLTN DRENC
//