ID A5L2U9_VIBBS Unreviewed; 449 AA.
AC A5L2U9;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDK27927.1};
GN ORFNames=VSWAT3_19063 {ECO:0000313|EMBL:EDK27927.1};
OS Vibrionales bacterium (strain SWAT-3).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales.
OX NCBI_TaxID=391574 {ECO:0000313|EMBL:EDK27927.1, ECO:0000313|Proteomes:UP000004912};
RN [1] {ECO:0000313|EMBL:EDK27927.1, ECO:0000313|Proteomes:UP000004912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SWAT-3 {ECO:0000313|EMBL:EDK27927.1,
RC ECO:0000313|Proteomes:UP000004912};
RA Azam F., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDK27927.1}.
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DR EMBL; AAZW01000028; EDK27927.1; -; Genomic_DNA.
DR AlphaFoldDB; A5L2U9; -.
DR Proteomes; UP000004912; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR30566:SF5; MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..130
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 255..320
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
SQ SEQUENCE 449 AA; 51097 MW; 73C79A69B29258A0 CRC64;
MIIKSALKFM THEAIVLSVI FINAVVMVAL ETTPTLPKTI GYWILWVDFV CVLYFTVELG
VKWTDLGTKG YFSDNWNKLD FLIVILSIPV LIEPFLSGGI GWLGDMAILR LARFLRLWRI
LRYVYTSETY KCLRIPVILL IVLTAFTMLI DSSKDLISDI YPQIKLTLNV LLVLSLTFLL
VRMLRVLFST FFHRKLTQNP YNFDSSLVDF ICLIAVVLTS LNGIMIAIST AGHDPFALLA
GLGIGGMAIA FAAQDAVANI IAGIMLLVQK PFRTGDWICI NGNTGAVHHI GLRCTVLEEF
GGEHLTFPNK IFMDSPVRNI DKRGFYLLSG SIRLHHKTKH NEINEVIDMM KKICTEHPEL
YNDCGVRFEG FGEACFPVSF WMCVKEWSQS EQIIYRDRWE KIRVVEQDFY IKLVKGINEK
GITCAMPIRE MVEENKTSPL TEKDGYHEN
//
