ID A5N448_CLOK5 Unreviewed; 462 AA.
AC A5N448;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Predicted reverse transcriptase/maturase family protein {ECO:0000313|EMBL:EDK35894.1};
GN OrderedLocusNames=CKL_3918 {ECO:0000313|EMBL:EDK35894.1};
OS Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK35894.1, ECO:0000313|Proteomes:UP000002411};
RN [1] {ECO:0000313|EMBL:EDK35894.1, ECO:0000313|Proteomes:UP000002411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC {ECO:0000313|Proteomes:UP000002411};
RX PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA Hagemeier C., Thauer R.K., Gottschalk G.;
RT "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT metabolic features.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
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DR EMBL; CP000673; EDK35894.1; -; Genomic_DNA.
DR RefSeq; WP_012104231.1; NC_009706.1.
DR AlphaFoldDB; A5N448; -.
DR STRING; 431943.CKL_3918; -.
DR KEGG; ckl:CKL_3918; -.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_3_1_9; -.
DR Proteomes; UP000002411; Chromosome.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd01651; RT_G2_intron; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR024937; Domain_X.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33642; COX1/OXI3 INTRON 1 PROTEIN-RELATED; 1.
DR PANTHER; PTHR33642:SF4; COX1_OXI3 INTRON 1 PROTEIN-RELATED; 1.
DR Pfam; PF01348; Intron_maturas2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:EDK35894.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002411};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:EDK35894.1};
KW Transferase {ECO:0000313|EMBL:EDK35894.1}.
FT DOMAIN 1..295
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 462 AA; 54232 MW; 3864A52ADABC5260 CRC64;
MQKAELILAI LKDKSNNNPN YKFQRIYRYL FNIDFYFRAY SQVYSAGENI GNVVTEKVHS
FNNEGVHKII EKLKNESYCP ESLEKSDKQN KKHSQIKGLY DNLIQQIIVE ILQSIYNVNF
SVNSHAFIPN KNCHTALYKI KTTCSGARWA VKGNIESCFY NINYDFVIKS LCEKISDGRF
INLIRKFLAA GYTKEKKNCD TWSGISQRES LANILINIYL DKFDKYINKE FGQVKYTRYL
DNFIIFISGT KDLAEYMIEK IKVFLKDKLN IETTEEEIFI IDLNKQRVKF LGYEITKLKH
NFKDNKTDKS KEKMDNEIIQ LLIPAEVIRK RIKPFILNGK PIHNNSRINL SVFKIISLYN
REIIDLYNYY CLASDVNAKV RKFKFYHYLS LVKTLARKEQ ISVKQVINRY GIVFKGKDKN
VLKKVVGINH MTKNGIKTII YCNESLKRKS KPLANVNDII WK
//
