ID A5TTU9_FUSNP Unreviewed; 301 AA.
AC A5TTU9;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN Name=galF {ECO:0000313|EMBL:EDK88324.1};
GN ORFNames=FNP_0516 {ECO:0000313|EMBL:EDK88324.1};
OS Fusobacterium polymorphum ATCC 10953.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=393480 {ECO:0000313|EMBL:EDK88324.1};
RN [1] {ECO:0000313|EMBL:EDK88324.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10953 {ECO:0000313|EMBL:EDK88324.1};
RA Qin X., Weinstock G.M.;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDK88324.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10953 {ECO:0000313|EMBL:EDK88324.1};
RA Karpathy S.E., Xiang Q., Gioia J., Jiang H., Liu Y., Petrosino J.F.,
RA Yerrapragada S., Fox G.E., Kinder Haake S., Weinstock G.M.,
RA Highlander S.K.;
RT "Genome sequence of Fusobacterium nucleatum subspecies polymorphum - a
RT genetically tractable Fusobacterium.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
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DR EMBL; CM000440; EDK88324.1; -; Genomic_DNA.
DR AlphaFoldDB; A5TTU9; -.
DR eggNOG; COG1210; Bacteria.
DR HOGENOM; CLU_029499_1_2_0; -.
DR Proteomes; UP000001921; Chromosome.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259,
KW ECO:0000313|EMBL:EDK88324.1};
KW Transferase {ECO:0000256|RuleBase:RU361259, ECO:0000313|EMBL:EDK88324.1}.
FT DOMAIN 13..275
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 301 AA; 33875 MW; 7C5F66FA7B7C07EB CRC64;
MSLKEAFMKK VTKAVIPAAG LGTRVLPATK ALPKEMLTIV DKPSLQYIVE ELVASGITDI
VIITGRNKNS IEDHFDFSYE LENTLKNDHK SELLDKVSHI SNMANIYYVR QNMPLGLGHA
ILKAKSFIGD EPFVIALGDD IIYNPEKPVT KQMIEKYEVY GKSIIGCQEV AKEDVSKYGI
AKLGDRFDEA TYQMLDFLEK PSLDSAPSRT ACLGRYLLLG KVFKYLEETK PGKNGEIQLT
DGILAMMKDN EEVLAYNFIG KRYDIGSKFG LLKANIEFGL RNEETKEDIK EYLKNLDIEK
I
//
