ID A5X6J7_ORYLA Unreviewed; 410 AA.
AC A5X6J7;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Wilms' tumor suppressor 1b {ECO:0000313|EMBL:ABG36854.1};
GN Name=Wt1b {ECO:0000313|EMBL:ABG36854.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|EMBL:ABG36854.1};
RN [1] {ECO:0000313|EMBL:ABG36854.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Carbio {ECO:0000313|EMBL:ABG36854.1};
RA Kluever N., Driessle J., Schartl M.;
RT "Divergent expression pattern of Wt1a and Wt1b in Medaka.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC -!- SIMILARITY: Belongs to the EGR C2H2-type zinc-finger protein family.
CC {ECO:0000256|ARBA:ARBA00005682}.
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DR EMBL; DQ647438; ABG36854.1; -; mRNA.
DR RefSeq; NP_001098390.1; NM_001104920.1.
DR AlphaFoldDB; A5X6J7; -.
DR GeneID; 100125521; -.
DR KEGG; ola:100125521; -.
DR CTD; 568416; -.
DR OrthoDB; 2898220at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR000976; Wilms_tumour_N.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23235:SF120; KRUEPPEL-LIKE FACTOR 15; 1.
DR PANTHER; PTHR23235; KRUEPPEL-LIKE TRANSCRIPTION FACTOR; 1.
DR Pfam; PF02165; WT1; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 284..313
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 314..343
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 344..371
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 375..404
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 410 AA; 45422 MW; 826DCFD930AD756B CRC64;
MSVGSDVCDL TLLPSAPPMP SLPGAVGSCG MSVGSGQWTN LLDLHPGSPY SSLNSHHSLI
KQEPGWGTAD PMEDPHCGLG AFTVHFSGQL TGSGPCRVGA FGEPVSQPRM FPNAAYLPSC
MDSSPLPRNQ GYGPLALDSN PGYSHSASHH NPQLSSLSFK HEDTLSPTNN IDQQYPTLNP
MFGCHNPSES TPNSQTLLLR NYSSDNLYQM ASQLECVTWN QMNTLASPTK TGQAASFDSD
PMLVSAQYHI HTHGVFRGLQ DIRRVPGVTP PVAKSSEASE RRPFVCVYPG CSKRYFKLSH
LQMHGRKHTG EKPYQCDVTE CGRRFSRSDQ LKRHQRRHTG VKPFQCQTCQ RKFSRSDHLK
THTRTHTGKT SEKPFTCRWS NCQKKFARSD ELVRHHSMHQ RNLSKLQPAI
//
