ID A5XEM2_MEDTR Unreviewed; 1118 AA.
AC A5XEM2;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Importin beta-3, putative {ECO:0000313|EMBL:AES80853.1};
DE SubName: Full=Putative RNA binding protein {ECO:0000313|EMBL:ABK28849.1};
DE SubName: Full=Putative TOG domain-containing protein {ECO:0000313|EMBL:RHN47476.1};
GN Name=RAN BP {ECO:0000313|EMBL:ABK28849.1};
GN Synonyms=11436838 {ECO:0000313|EnsemblPlants:AES80853};
GN OrderedLocusNames=MTR_7g085820 {ECO:0000313|EMBL:AES80853.1};
GN ORFNames=MtrunA17_Chr7g0253431 {ECO:0000313|EMBL:RHN47476.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:ABK28849.1};
RN [1] {ECO:0000313|EMBL:ABK28849.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17449807; DOI=10.1105/tpc.106.048264;
RA Middleton P.H., Jakab J., Penmetsa R.V., Starker C.G., Doll J., Kalo P.,
RA Prabhu R., Marsh J.F., Mitra R.M., Kereszt A., Dudas B., Vandenbosch K.,
RA Long S.R., Cook D.R., Kiss G.B., Oldroyd G.E.;
RT "An ERF transcription factor in Medicago truncatula that is essential for
RT Nod factor signal transduction.";
RL Plant Cell 19:1221-1234(2007).
RN [2] {ECO:0000313|EMBL:AES80853.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES80853.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES80853,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [3] {ECO:0000313|EMBL:AES80853.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES80853,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [4] {ECO:0000313|EnsemblPlants:AES80853}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES80853};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [5] {ECO:0000313|EMBL:RHN47476.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN47476.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DQ984942; ABK28849.1; -; Genomic_DNA.
DR EMBL; CM001223; AES80853.1; -; Genomic_DNA.
DR EMBL; PSQE01000007; RHN47476.1; -; Genomic_DNA.
DR RefSeq; XP_003624635.1; XM_003624587.2.
DR AlphaFoldDB; A5XEM2; -.
DR STRING; 3880.A5XEM2; -.
DR PaxDb; 3880-AES80853; -.
DR EnsemblPlants; AES80853; AES80853; MTR_7g085820.
DR GeneID; 11436838; -.
DR Gramene; AES80853; AES80853; MTR_7g085820.
DR KEGG; mtr:11436838; -.
DR eggNOG; KOG2171; Eukaryota.
DR HOGENOM; CLU_003794_0_1_1; -.
DR OMA; DSCYQDD; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR Proteomes; UP000265566; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527:SF102; BETA-3, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 371..612
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 422..460
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1118 AA; 123784 MW; E6390BEA3E8D3CDE CRC64;
MALNDQNQAQ MALILGPDST HFESLITNLM STINDQRSQA ENLFNLCKQT YPDSLILKLS
HLLHTSSNPE TRTMSTILLR RHLTRHHDDS FIYPHLSPST QSTLRSLLLS SLHQEPIKSI
VKKLCDTVSE LASALLSDDL SSWPDLLPLL FQWVTSNDAR LQEIALLVFA QLAHYIGETL
LPQLSTLHSV FLRCLSAATS SSDVRIAALA ASINFVQCLS NSSDRDRFQD LLPLMMQTLT
EALNSGQEAT AQEALELLIE LAGTEPRFLR RQIVDIVGAM LQIAEAESLE EGTRHLAIEF
VVTLAEARER APGMMRKLPQ FVKKLFGVLM NLLLDIEDDP AWHAAVSEDD DAGETSNYGF
GQECLDRLSI ALGGNTIVPV ASELLPTYLA APEWQKHHAA LVALAQIAEG CSKVMTKNLE
HVLSMVLNSF PDPNPRVRWA AINAIGQLST DLGPDLQDKY HHLVLPALAG AMDDFQNPRV
QAHAASAVLN FTENCTPDIL VPYLDGIVSK LLVLLQSGKQ MVQEGALTAL ASVADSSQEK
FQKYYDAVIP YLKAILLNAN DKSNRMLRAK AMECISLVGM AVGKEKFRDD AKQVMDVLMS
LQQSQLDSDD PTASYMLQAW ARLCKCLGQD FLPYMGFVMP PLLQSAQLKP DVSITSADSD
AEFDEDDDSI ETITLGDKRI GIKTSVLEEK ATACNMLCCY ADELKEGFFP WIDQVASTLV
PLLKFYFHEE VRKAAASAMP ELLSSAKWAI EKGQSQGRDA TYLKQLSDYI IPNLVEALHK
EPEVEICASM LGALNECIQV SGPHLDEKQV RSIVDEIKQV ITASSSRKHE RAERAKEEDF
DAEERELLKE ENELEEELFD QIGDCLGTLT KTFRASFLPF FEELSSYLIP MFGKDKTSEE
RRIAICIFDD IAEHCREAAH KYYGSFLPFL LEACNDECSD VRQAAVYGVG VCAEFGGSVF
KPLVGEALSR LNAVITHPNA QHSDNVMAYD NAVSALGKIC QFHRDSINAA QVVPAWLSCL
PIKGDLIEAK VVHDLLCSMV ERSDKELIGH NNQYLSKIVA IFAEILCAGT DLATEQTVSR
MINLLRQLQQ TLPPSTLAST WSSLHPQQQL ALQSILSS
//
