ID A6EM45_9BACT Unreviewed; 364 AA.
AC A6EM45;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Thiamine biosynthesis protein (HesA/MoeB/ThiF family protein) {ECO:0000313|EMBL:EDM45645.1};
GN ORFNames=SCB49_07547 {ECO:0000313|EMBL:EDM45645.1};
OS unidentified eubacterium SCB49.
OC Bacteria; Bacteroidota; environmental samples.
OX NCBI_TaxID=50743 {ECO:0000313|EMBL:EDM45645.1, ECO:0000313|Proteomes:UP000003659};
RN [1] {ECO:0000313|EMBL:EDM45645.1, ECO:0000313|Proteomes:UP000003659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCB49 {ECO:0000313|EMBL:EDM45645.1,
RC ECO:0000313|Proteomes:UP000003659};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM45645.1}.
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DR EMBL; ABCO01000001; EDM45645.1; -; Genomic_DNA.
DR AlphaFoldDB; A6EM45; -.
DR STRING; 50743.SCB49_07547; -.
DR Proteomes; UP000003659; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00158; RHOD; 1.
DR CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF102; ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF00899; ThiF; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003659};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 282..363
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT COILED 265..292
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 364 AA; 40524 MW; 665AC92E725676D3 CRC64;
MKTLTEAEKV QYSRHLLLND VGESGQLKLK AAKVLVIGAG GLGCPIIQYL TASGVGTIGI
VDDDIVSTSN LQRQVLYDIT EIGNPKVNVV ITKMKQLNPH ISFKGFKQRL TRENALDIIS
NFDLVIDGCD NFQTRYLVND ACIILNKPWI FGAIFKFNGQ LSVFNYKNGP SYRCLFPEPP
STGETPACNE AGVLGILPGI LGTKMASEGL KLILGLGKLL SGKLQLINIL ESSIQTVQFE
RNQKNFQIKI LAKNYNAFCG LPTRADRASI TSEMLQKKLN EEKNNLQLLD VRTEEEYKAF
HLNNSIHIPL NELEDNYSLL DLSKETVIMC AKGRRSLEAV LYLKSKGFKK ILNLENGLNT
WQKT
//
