ID   A6ET57_9BACT            Unreviewed;       412 AA.
AC   A6ET57;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Probable Methionine gamma-lyase {ECO:0000313|EMBL:EDM43122.1};
GN   ORFNames=SCB49_11624 {ECO:0000313|EMBL:EDM43122.1};
OS   unidentified eubacterium SCB49.
OC   Bacteria; Bacteroidota; environmental samples.
OX   NCBI_TaxID=50743 {ECO:0000313|EMBL:EDM43122.1, ECO:0000313|Proteomes:UP000003659};
RN   [1] {ECO:0000313|EMBL:EDM43122.1, ECO:0000313|Proteomes:UP000003659}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCB49 {ECO:0000313|EMBL:EDM43122.1,
RC   ECO:0000313|Proteomes:UP000003659};
RA   Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDM43122.1}.
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DR   EMBL; ABCO01000010; EDM43122.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ET57; -.
DR   STRING; 50743.SCB49_11624; -.
DR   Proteomes; UP000003659; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11808:SF15; CYSTATHIONINE GAMMA-LYASE; 1.
DR   PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:EDM43122.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003659}.
FT   MOD_RES         217
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   412 AA;  44751 MW;  B4F0587CB28357F4 CRC64;
     MFTEIKNEPM SDNKNFKPAN NIQDLQYFGE FGGVNPSISD SSTYTFLSAK TMFDTFEGNA
     DGCYLYSRHS TPSNLYLGEA LAAMEGTETA NVAASGMGAI TPTILQFCQA GDHLVSSRTI
     YGGTYAFLKN FAPRLNISTS FVDITKLDVV EAAITPNTKA IFCECVSNPL LEIADIEGLS
     KIAKKHNLPL LVDNTFSPLS ISPAKLGADV IMHSLTKFIN GASDTMGGVV CGSQELIDTL
     RNVNDGACML LGASMDSLRA ASILKNLRTL HIRMQQHSKN GMYLAEKFEA DGLRTVYPGL
     KSHPGHELMK RQMNAQYGFG GMLTIDAGSL DKANALMELM QEKNLGYLAV SLGFYKTLFS
     APGSSTSSEI PEDEQREMGL SDGLIRFSIG LDADIERTYT MMRECMVQVG VL
//