ID A6LV51_CLOB8 Unreviewed; 874 AA.
AC A6LV51;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Pyruvate phosphate dikinase, PEP/pyruvate-binding {ECO:0000313|EMBL:ABR34231.1};
GN OrderedLocusNames=Cbei_2063 {ECO:0000313|EMBL:ABR34231.1};
OS Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium
OS acetobutylicum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=290402 {ECO:0000313|EMBL:ABR34231.1, ECO:0000313|Proteomes:UP000000565};
RN [1] {ECO:0000313|EMBL:ABR34231.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G.,
RA Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W.,
RA Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B.,
RA Blaschek H., Richardson P.;
RT "Complete sequence of Clostridium beijerinckii NCIMB 8052.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR34231.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=21962126; DOI=10.1186/1471-2164-12-479;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Single-nucleotide resolution analysis of the transcriptome structure of
RT Clostridium beijerinckii NCIMB 8052 using RNA-Seq.";
RL BMC Genomics 12:479-479(2011).
RN [3] {ECO:0000313|EMBL:ABR34231.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=22433311; DOI=10.1186/1471-2164-13-102;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Genome-wide dynamic transcriptional profiling in clostridium beijerinckii
RT NCIMB 8052 using single-nucleotide resolution RNA-Seq.";
RL BMC Genomics 13:102-102(2012).
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DR EMBL; CP000721; ABR34231.1; -; Genomic_DNA.
DR RefSeq; WP_012058290.1; NC_009617.1.
DR AlphaFoldDB; A6LV51; -.
DR KEGG; cbe:Cbei_2063; -.
DR eggNOG; COG0574; Bacteria.
DR eggNOG; COG3848; Bacteria.
DR HOGENOM; CLU_005950_0_0_9; -.
DR Proteomes; UP000000565; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.50.30.10; Phosphohistidine domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR InterPro; IPR036637; Phosphohistidine_dom_sf.
DR InterPro; IPR002192; PPDK_AMP/ATP-bd.
DR PANTHER; PTHR43615; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR43615:SF1; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR Pfam; PF00391; PEP-utilizers; 1.
DR Pfam; PF01326; PPDK_N; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52009; Phosphohistidine domain; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ABR34231.1};
KW Pyruvate {ECO:0000313|EMBL:ABR34231.1};
KW Transferase {ECO:0000313|EMBL:ABR34231.1}.
FT DOMAIN 18..317
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
FT DOMAIN 797..869
FT /note="PEP-utilising enzyme mobile"
FT /evidence="ECO:0000259|Pfam:PF00391"
SQ SEQUENCE 874 AA; 98814 MW; B4304708632E8F22 CRC64;
MNPYVLGFQE IDKTKLMIVG GKGANLGALS RINGILVPEG FCITTEAYKK IIGNNNEFNS
LLSELSLLNI ENIEKIGEIS GKIRKVIEEI EIPKDIDDEI TFYLSKFGER HAYAVRSSAT
AEDLPTASFA GQQDTYLNIM KKPSILKHIS KCWASLFTDR AVIYRMQNNF DHDKVHLSVV
IQKMVFPQAA GIMFTADPIT SNRKIVSIDA SFGLGEALVS GLVNSDIYKV QENKIINKKI
SAKKLAIYAL KEGGTEEREI EDERQNMQTL TDDQILQLEQ MGRKIESYFG RPQDIEWCLY
DDKFYVVQSR PITTLYPTPQ VNDNKNHVYL SFAHRQMMTE AMRPLGLSFF QIFFKQFGIQ
TNMPVIGGRL YMDISHDLAS PIARKLFISG LDKVDVLMKS ALINLQKRKE YLKSLPKGKT
SLNVEGGILS FGIQMIKEYL RNDPSFVEKS VAENQVLLSN KEKIFSSISG EELFDFIVKD
MNDIKAAMLK VYGAYFAGSY ASNWINKNMK KWLDEKSVAD TLAQSVSNNV TSEMGLELLD
VADVIRQYPS VIKYLENAKR ETFFEDLSKI DGGNIVSDSI HNYLKKYGMR CSGEIDITRT
RWNEDPMLLV PLILSNIKNF EPNAHSAKFD QGLLEAKQKE AEILSRLKQL PGSNRKLKKT
KKVISVLRNF AGYREYNKYL LICYFWIVKQ ALLKEAETLK QDDVIKDIDD IYYLTFDELK
EAVKTKHVDY SIITKRKEEY EIYKKLTPPR IMTSDGEIIS GEYDTGNMPK GAIAGTPVSS
GIVEGRARVI LNMNEAKIEE GDILITKFTD PSWTPIFVLV KGLVTEVGGM MTHGAVVARE
YGLPAVAGVD DATKLIKDGE RIRINGTEGY IEIL
//
