ID A6Q3H9_NITSB Unreviewed; 302 AA.
AC A6Q3H9;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Fructose-bisphosphate aldolase, class I {ECO:0000313|EMBL:BAF70038.1};
DE EC=4.1.2.13 {ECO:0000313|EMBL:BAF70038.1};
GN OrderedLocusNames=NIS_0927 {ECO:0000313|EMBL:BAF70038.1};
OS Nitratiruptor sp. (strain SB155-2).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Nautiliales;
OC Nitratiruptoraceae; Nitratiruptor.
OX NCBI_TaxID=387092 {ECO:0000313|EMBL:BAF70038.1, ECO:0000313|Proteomes:UP000001118};
RN [1] {ECO:0000313|EMBL:BAF70038.1, ECO:0000313|Proteomes:UP000001118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB155-2 {ECO:0000313|EMBL:BAF70038.1,
RC ECO:0000313|Proteomes:UP000001118};
RX PubMed=17615243; DOI=10.1073/pnas.0700687104;
RA Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K.,
RA Horikoshi K.;
RT "Deep-sea vent epsilon-proteobacterial genomes provide insights into
RT emergence of pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007).
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DR EMBL; AP009178; BAF70038.1; -; Genomic_DNA.
DR RefSeq; WP_012082301.1; NC_009662.1.
DR AlphaFoldDB; A6Q3H9; -.
DR STRING; 387092.NIS_0927; -.
DR KEGG; nis:NIS_0927; -.
DR eggNOG; COG1830; Bacteria.
DR HOGENOM; CLU_057069_2_2_7; -.
DR InParanoid; A6Q3H9; -.
DR OrthoDB; 5915071at2; -.
DR Proteomes; UP000001118; Chromosome.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR PANTHER; PTHR47916:SF3; FRUCTOSE-BISPHOSPHATE ALDOLASE_6-DEOXY-5-KETOFRUCTOSE 1-PHOSPHATE SYNTHASE; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:BAF70038.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001118}.
FT ACT_SITE 175
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 206
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 302 AA; 33443 MW; 132090C98BCE471F CRC64;
MNLEKLIPAD VPPEKKGEFL AHLQETTNGT GRLMLFAGDQ KVEHLNNDFY GPGIPLEDNN
PEHLFKIASK AKVGVFATQF GLISRYAPDY KKIPYLIKLN SKTNIIPYSA KDPYSQQWIE
VEEAIEFARY SGINLQGFGY TVYLGSEHEH SMLTEAANIV HTAHKHGYLA VLWMYPKGNF
VKDEHDPHLI AGAAGVALCL GADFAKVKVP YKDGKFIPEL LIEATVAAGN CGVLCEGGKK
IDERTFLQEL YDQIHIGGTR GNGTGRNIHQ RPLEEAIKMA NAIYAITCED KSVDEAIKIL
EA
//
