ID A6R3E3_AJECN Unreviewed; 407 AA.
AC A6R3E3;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=Tyrosine specific protein phosphatases domain-containing protein {ECO:0000259|PROSITE:PS50056};
GN ORFNames=HCAG_04151 {ECO:0000313|EMBL:EDN07641.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN07641.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476658; EDN07641.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R3E3; -.
DR STRING; 339724.A6R3E3; -.
DR VEuPathDB; FungiDB:HCAG_04151; -.
DR HOGENOM; CLU_057546_2_0_1; -.
DR OMA; MPEEYAT; -.
DR OrthoDB; 933109at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR026893; Tyr/Ser_Pase_IphP-type.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR31126:SF10; PROTEIN PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06650)-RELATED; 1.
DR PANTHER; PTHR31126; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13350; Y_phosphatase3; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 186..231
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 90..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 43878 MW; 40FC530A75B06A3E CRC64;
MSPHEPIPRA LNANIDIARN SDAATVKPAV RIHSPDLRFE SILNFRDGDE RGCFIPKRKE
ADRHRLAEEL HLASVIDLRS TTEHNIAANR HLASQPSRPN RPKDGPTPVV QTQPTANDEH
LVQLPGVRRI MISLAGWGLE KLLLWRLSWF NLLKAIVLLA SGYRNAATKL VVEQAMVPRG
LKGLAHDTLT ASQAEIKELF EHLGNPAVYP TLVHCTQGKD RTGLVVILLL LLAGSPAGED
GGKRERMGDG DGRKSNNDDD SDDDDDSDSN NNNNTGEGLG GDGGRYGHVQ GDISKLGPDA
DTAPAPAPAA DPDTGTGTGT GTSPQIPLSA IASDYRKSEG ELLPELQERL AEMRAIGMPE
EYATCPDGFT EDVVRFLEEG YGGIRGYLRA VGVDDGVVER VRGLLVA
//
