ID A6R4D8_AJECN Unreviewed; 251 AA.
AC A6R4D8;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=Glutamine amidotransferase domain-containing protein {ECO:0000259|Pfam:PF00117};
GN ORFNames=HCAG_04496 {ECO:0000313|EMBL:EDN07986.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN07986.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476658; EDN07986.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R4D8; -.
DR STRING; 339724.A6R4D8; -.
DR VEuPathDB; FungiDB:HCAG_04496; -.
DR HOGENOM; CLU_054974_0_2_1; -.
DR OMA; PWIQTLK; -.
DR OrthoDB; 4899at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01741; GATase1_1; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR044992; ChyE-like.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR PANTHER; PTHR42695; GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED; 1.
DR PANTHER; PTHR42695:SF5; GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED; 1.
DR Pfam; PF00117; GATase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 52..204
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT ACT_SITE 113
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 199
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 201
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 251 AA; 27901 MW; 5A217A6BFDCED98D CRC64;
MSTPLRIAVL ECDTPLDRTK SRYGSYGGVF ESLLQASVKL LNQSDKINPV TELDISKWDV
VESDKYPSLE NIDAVLITGS KHNSYDDIPW INRLVDFISK ILTQDRVRII GVCFGHQILG
RALGAKVGPN EQGWEISVHD MNLTDKGKEL FGTNKLCLQQ MHRDVVHYCP SNVTLLGSSS
ICDVQGMYIP GHFISVQGHP EFTKDIVAEI LDARHDAGIF SSEIYEDGVA RLGNEHDGLL
VGKAFLEFLI N
//
