ID A6TGX3_KLEP7 Unreviewed; 807 AA.
AC A6TGX3;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000256|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000256|HAMAP-Rule:MF_01430};
GN ORFNames=KPN_04452 {ECO:0000313|EMBL:ABR79807.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR79807.1, ECO:0000313|Proteomes:UP000000265};
RN [1] {ECO:0000313|EMBL:ABR79807.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2] {ECO:0000313|EMBL:ABR79807.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. Constitutes, with BamD, the core component of the
CC assembly machinery. {ECO:0000256|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC {ECO:0000256|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004442, ECO:0000256|HAMAP-Rule:MF_01430}.
CC Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000256|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; CP000647; ABR79807.1; -; Genomic_DNA.
DR RefSeq; WP_004186501.1; NC_009648.1.
DR AlphaFoldDB; A6TGX3; -.
DR SMR; A6TGX3; -.
DR STRING; 272620.KPN_04452; -.
DR PaxDb; 272620-KPN_04452; -.
DR EnsemblBacteria; ABR79807; ABR79807; KPN_04452.
DR KEGG; kpn:KPN_04452; -.
DR HOGENOM; CLU_007664_1_0_6; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.310; membrane protein fhac; 5.
DR Gene3D; 2.40.160.50; membrane protein fhac: a member of the omp85/tpsb transporter family; 1.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR NCBIfam; TIGR03303; OM_YaeT; 1.
DR PANTHER; PTHR12815:SF23; OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMA; 1.
DR PANTHER; PTHR12815; SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01430};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01430};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|HAMAP-Rule:MF_01430};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_01430};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01430};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452,
KW ECO:0000256|HAMAP-Rule:MF_01430}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01430"
FT CHAIN 21..807
FT /note="Outer membrane protein assembly factor BamA"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01430"
FT /id="PRO_5009007059"
FT DOMAIN 24..91
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 92..172
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 175..263
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 266..344
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 347..421
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
SQ SEQUENCE 807 AA; 89033 MW; C237A6C6522E9884 CRC64;
MLKKTHIISG LLITPLTLYA ATSYQVDDIR FEGLQRVTVG AALLSMPLHA GDAVTPEDVS
EAVRALYASG NFENVQILRD GKTLVVQVKE RPTIASVSFS GNKAVKDDAL KENLTASGIS
AGSALDRNSL SEIEKGLQDF YYSAGKYSAQ VHAVVTPLPR NRVDLTFVFQ EGISAKIAQI
NIIGNQAFRE ETLLDQLQLR DNVPWWNVVA DKKYQKQKLE ADLETLRSFY LDRGYARFAI
ESTQVSMTPD KKSLYITIAL NEGERYRVDR TQVTGDLAQH GPEIEALAQP LAGAWYSGAQ
VTTVENEIKK HFGKYGYAWP QVTSTPEIDD AHHRVVLHIQ VNAGRRYSVR QIRFSGNDTS
RDAVLRREMR QMEGAWLNNE KVDQGKVRLD RTGFFENVEQ QIVPVNGTAD QVDVVYKVKE
RNTGSFNVGL GFGTDSGVSY QLGVTQDNWL GTGNSVSFNG TRNSYQSYLE LGATNPWFTV
DGISLGGKIF YNSYDASDAD AGSYNQQSYG LGSTLGFPIS ENNSLNLGLD YVHNRLTNMD
PELTTWRYLS SRGIEPSVVT KDGDSGAKYS ANDYFVSLGW GYNDLDRGFF PRAGNKSSLS
GKVTLPGSDN SYYKLSFDTA QYLPLSENKR WVWMERLRAG YAGGLDGKSV PFYDNFYAGG
SSSVRGFSSN TIGPKAAYYR CNGSESSYSA CPLDASSDAV GGNAMAVLNS EFIIPTPFVN
DKYADSLRTS LFVDAGTVWS TSWHNTAQTL AAGIPDYGDP SHIRLSAGIA VQWMSPLGPL
VFSWAEPFKK YDGDKAEQFQ FNIGKTW
//
