ID A6TL36_ALKMQ Unreviewed; 411 AA.
AC A6TL36;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=FAD-dependent pyridine nucleotide-disulphide oxidoreductase {ECO:0000313|EMBL:ABR46904.1};
GN OrderedLocusNames=Amet_0679 {ECO:0000313|EMBL:ABR46904.1};
OS Alkaliphilus metalliredigens (strain QYMF).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Alkaliphilus.
OX NCBI_TaxID=293826 {ECO:0000313|EMBL:ABR46904.1, ECO:0000313|Proteomes:UP000001572};
RN [1] {ECO:0000313|Proteomes:UP000001572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QYMF {ECO:0000313|Proteomes:UP000001572};
RX PubMed=27811105; DOI=10.1128/genomeA.01226-16;
RA Hwang C., Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina Del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F.,
RA Land M.L., Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J.,
RA Richardson P., Fields M.W.;
RT "Complete genome sequence of Alkaliphilus metalliredigens strain QYMF, an
RT alkaliphilic and metal-reducing bacterium isolated from borax-contaminated
RT leachate ponds.";
RL Genome Announc. 4:0-0(2016).
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DR EMBL; CP000724; ABR46904.1; -; Genomic_DNA.
DR RefSeq; WP_011971812.1; NC_009633.1.
DR AlphaFoldDB; A6TL36; -.
DR STRING; 293826.Amet_0679; -.
DR KEGG; amt:Amet_0679; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_3_9; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000001572; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001572}.
FT DOMAIN 3..95
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 111..392
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 411 AA; 45445 MW; 38C11024B0CDF3B6 CRC64;
MSKHVVDEAQ RCLQCKKPAC RKGCPIDTPI PEFINSLLGG DIRASGEMLF RNNPLSVICS
LVCPHEKQCE GNCILGKKSN PVHISAIENY ISDYSLDIMD LKPKEKLEGN IGIIGAGPAG
ITIAFILALK GYNITIFEAN DRIGGVLRYG IPEFRLPKDI LERLKYKLVR LGVTIRPNTL
IGPVLTVEDL FRDGFDALFI GTGVWKPKKI NIKGESLGHV HYAIDYLKNP EVYDLGEKVC
IVGAGNVAMD VARTALRKGA KEVSIMYRKG TEDMPAREYE IQYAKIDGVK FELFKTPVEF
TKQGVRYVKT EENNDEGEIN NTHNPRGIFE CDSVIVSISQ GPKANVVSNT KGIEISHYGL
VITDEHGRTT REGVFASGDV VTGAKTVVEA VRFSKEVAEV IHQYVAKKYD L
//
