ID A6UN01_SINMW Unreviewed; 8915 AA.
AC A6UN01;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Amino acid adenylation domain {ECO:0000313|EMBL:ABR65031.1};
GN OrderedLocusNames=Smed_6473 {ECO:0000313|EMBL:ABR65031.1};
OS Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OG Plasmid pSMED03 {ECO:0000313|EMBL:ABR65031.1,
OG ECO:0000313|Proteomes:UP000001108}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=366394 {ECO:0000313|EMBL:ABR65031.1, ECO:0000313|Proteomes:UP000001108};
RN [1] {ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|Proteomes:UP000001108};
RC PLASMID=Plasmid pSMED03 {ECO:0000313|Proteomes:UP000001108};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA Richardson P.;
RT "Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED03.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR65031.1, ECO:0000313|Proteomes:UP000001108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM419 {ECO:0000313|EMBL:ABR65031.1,
RC ECO:0000313|Proteomes:UP000001108};
RC PLASMID=Plasmid pSMED03 {ECO:0000313|Proteomes:UP000001108};
RX PubMed=21304680; DOI=10.4056/sigs.43526;
RA Reeve W., Chain P., O'Hara G., Ardley J., Nandesena K., Brau L., Tiwari R.,
RA Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA Hauser L., Chang Y.J., Ivanova N., Mavromatis K., Markowitz V.,
RA Kyrpides N., Gollagher M., Yates R., Dilworth M., Howieson J.;
RT "Complete genome sequence of the Medicago microsymbiont Ensifer
RT (Sinorhizobium) medicae strain WSM419.";
RL Stand. Genomic Sci. 2:77-86(2010).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP000741; ABR65031.1; -; Genomic_DNA.
DR RefSeq; YP_001314964.1; NC_009622.1.
DR KEGG; smd:Smed_6473; -.
DR PATRIC; fig|366394.8.peg.3001; -.
DR HOGENOM; CLU_222724_0_0_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000001108; Plasmid pSMED03.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 4.
DR CDD; cd12116; A_NRPS_Ta1_like; 1.
DR CDD; cd19544; E-C_NRPS; 7.
DR CDD; cd08649; FMT_core_NRPS_like; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 8.
DR Gene3D; 3.40.50.12230; -; 1.
DR Gene3D; 3.40.50.980; -; 10.
DR Gene3D; 1.10.1200.10; ACP-like; 8.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 8.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 3.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 8.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 8.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 8.
DR Pfam; PF13193; AMP-binding_C; 8.
DR Pfam; PF00668; Condensation; 8.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR Pfam; PF00550; PP-binding; 8.
DR SMART; SM00823; PKS_PP; 8.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 8.
DR SUPFAM; SSF47336; ACP-like; 8.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 16.
DR SUPFAM; SSF53328; Formyltransferase; 1.
DR PROSITE; PS00455; AMP_BINDING; 8.
DR PROSITE; PS50075; CARRIER; 8.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plasmid {ECO:0000313|EMBL:ABR65031.1}.
FT DOMAIN 1196..1270
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2288..2362
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3380..3454
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4475..4549
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5560..5634
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 6645..6719
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7735..7809
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8820..8895
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 8915 AA; 965681 MW; FC35D6A39FCD4578 CRC64;
MIDLWLPKSP HGYGLCGQDP RYSSTTRTLS AIFVGGGSLI IGCAQTAKEM GCSIPAVLPT
DDVFRAWATN LGIRCFDNVE QTYEFLHDVN VDLIFSVVNP FILPAHLLER ARVGAFNYHD
SPLPRHAGTH ATSWAILAQE SQYAISWHHI NSGIDTGNVV VQCPLSVAST DTAMTLNLKC
YDAAIEGFRA LLAMIIAGAD LQGSPQTVPV IMPVGRDGAL PLSYSQQRLW FLAQLDEDST
NYNIPLGWRL QGRLDRVAWR RSLDRLFARH EALRCTFVAG EDDPQVQILS GDRGLPVVEH
DLRDRPDAQA ALLDLCQEEA RTPFDLAREP LIRGRLIRLA DEEHVFLLTQ HHIVSDGWSL
GVLVRELSSL YRAFEAGEDD PLPPLAIQYP DYAAWQRQWL SGERLQRQAQ YWRDTLSGAP
ARLALPTDRP RPAQQSFAGA SVPVVIDQVL TRGLKRLSRQ HGTTLFMTVL AAWAAVLSRL
SGQDDIVIGV PTANRRRREI EDLIGFFVNT LAVRIDLSGE PSVSDLLERA RRAALTAQDH
QDLPFEQVVE IVQPPRALDH TPLFQVGLAW QNNTGGSLDL PGLRVEAAGE GLDQVKFDLE
LNLGEQGEAI AGTLGYATAL FDRATIERQC GYLLALLRAM LADAEQPVSE LDILPPDERS
YLLEELNRTE TDYPSDLCVH ALFEAQVRRA PDAVALVFEE QSISYGALNA DANRLAHHLI
GLGVRPDQPV AICVERSPAM VVGLLAILKA GGAYVPLDPA YPSERLRQLL DDAGPRLLLC
DAAGRAALGA EAIADLSAVD LDAVTAWADQ SADDPDPHAL GLTARNLAYV IYTSGSTGTP
KGVMVEHRGM TNYLSWARES YAPTSSSVVS SSLAFDATVN SLFAPLVSGG HALLTKEGDE
VEGIRSRVGT PCGLVNVTPS HLDVLGQQLQ LAGDASQVEV LVIGGEALSS STVELWRQIQ
PAARMVNEYG PTEAVVGCAF HDIPADLSAS TNVPIGRPIA NTRIYLLDGH GQPVPFGAVG
ELYIGGAGVA RGYLNRPDLT AERFLADPFS GKAGARMYRS GDLARYLPDG NLEFLGRNDD
QVKIRGFRIE PGEIAARLLE HELVGDAAVV AHADAAGDKR LVAYVVAKTT DGSAEADGAG
LAASLRAHLG GLLPDYMVPS AFVRLDALPL TVNGKLDRKA LPVPDDDAYA RRAYEAPQGE
IETLLAGIWA ELLGVERVGR HDNFFELGGH SLLTVQMMER LRRLSLGVEV RTVFAKPMLA
DLAASLGSHR EVAVPANPIT EQSTAITPQM LPLIDLTQPE IDRIVSTVPG GVGNIQDIYG
LSPLQDGILF HHLLATQGDP YLLVSQMAFA ERGVLDRYLA AVQQVVDRHD ILRTAFVWEG
LSSPAQVVWR KAALDVLEVE LEGCDGSGAD ELRRRFDPRQ YRLDLGRAPL MRFVIAREPG
SGRWLLLVLQ HHLIGDHTTA EVMHAEVRAV LQGRAHELAA PQPFRNLVAQ ARLGMDAKAH
EAFFREMLAD IDEPTLPFAL SEVYGDGRGS REARRMLPQA LNDRLRHQAR RLGVSLASLC
HLAWAQVVAL SSGREQVVFG TVLFGRMHAG AGADRAMGLF MNTLPLRLDL DETGVEESVR
IAHARLAELL SHEHASLALA QRCSDIAAPA PLFSALLNYR HNTPAMAGEG TSDVLSGMEW
LGGEERTNYP LTLSVDDFGQ ELGLTADAVE PISADQICGY MQRALEQLVD ALEQAPDRPV
RELDILPAEE RSYLLEELNR TEADYPSDLC VHALFEAQVR RAPDAVALVF EEQSISYGAL
NADANRLAHH LIGLGVRPDQ PVAICVERSP AMVVGLLAIL KAGGAYVPLD PAYPSERLRQ
LLDDARPRLL LCDAAGRAAL GAEAIADLSA VDLDAATAWA DQSADDPDPH ALGLTARNLA
YVIYTSGSTG TPKGVMVEHR GMTNYLSWAR ESYAPTSSSV VSSSLAFDAT VNSLFAPLVS
GGHALLTKEG DEVEGIRSRV GTPCGLVNVT PSHLDVLGQQ LQLAGDASQV EVLVIGGEAL
SSSTVELWRQ IQPAARMVNE YGPTEAVVGC AFHDIPADLS ASTNVPIGRP IANTRIYLLD
GHGQPVPFGA VGELYIGGAG VARGYLNRPD LTAERFLADP FSGKAGARMY RSGDLARYLP
DGNLEFLGRN DDQVKIRGFR IEPGEIAARL LEHELVGDAA VVAHADAAGD KRLVAYVVAK
TTDGSAEADG AGLAASLRAH LGGLLPDYMV PSAFVRLDAL PLTVNGKLDR KALPVPDDDA
YARRAYEAPQ GEIETLLAGI WAELLGVERV GRHDNFFELG GHSLLTVQMM ERLRRLSLGV
EVRTVFAKPM LADLAASLGS HREVAVPANP ITEQSTAITP QMLPLIDLTQ PEIDRIVSTV
PGGVGNIQDI YGLSPLQDGI LFHHLLATQG DPYLLVSQMA FAERGVLDRY LAAVQQVVDR
HDILRTAFVW EGLSSPAQVV WRKAALDVLE VELEGCDGSG ADELRRRFDP RQYRLDLGRA
PLMRFVIARE PGSGRWLLLV LQHHLIGDHT TAEVMHAEVR AVLQGRAHEL AAPQPFRNLV
AQARLGMDAK AHEAFFREML ADIDEPTLPF ALSEVYGDGR GSREARRMLP QALNDRLRHQ
ARRLGVSLAS LCHLAWAQVV ALSSGREQVV FGTVLFGRMH AGAGADRAMG LFVNTLPLRL
DLDETGVEES VRIAHARLAE LLSHEHASLA LAQRCSDIAA PAPLFSALLN YRHNTPAMAG
EGTSDVLSGM EWLGGEERTN YPLTLSVDDF GQELGLTADA VEPISADRIC GYMQRALEQL
VDALEQAPDR PVRELDILPA EERSYLLEEL NRTETDYPSD LCVHALFEAQ VRRAPDAVAL
VFEEQSISYG ALNADANRLA HHLIGLGVRP DQPVAICVER SPAMVVGLLA ILKAGGAYVP
LDPAYPSERL RQLLDDARPR LLLCDAAGRA ALGAEAIADL SAVDLDAATA WADQSADDPD
PHALGLTARN LAYVIYTSGS TGTPKGVMVE HRGMTNYLSW ARESYAPTSS SVVSSSLAFD
ATVNSLFAPL VSGGHALLTK EGDEVEGIRS RVGTPCGLVN VTPSHLDVLG QQLQLAGDAS
QVEVLVIGGE ALSSSTVELW RQIQPAARMV NEYGPTEAVV GCAFHDIPAD LSASTNVPIG
RPIANTRIYL LDGHGQPVPF GAVGELYIGG AGVARGYLNR PDLTAERFLA DPFSGKAGAR
MYRSGDLARY LPDGNLEFLG RNDDQVKIRG FRIEPGEIAA RLLEHELVGD AAVVAHADAA
GDKRLVAYVV AKTTDGSAEA DGAGLAASLR AHLGGLLPDY MVPSAFVRLD ALPLTVNGKL
DRKALPVPDD DAYARRAYEA PQGEIETLLA GIWAELLGVE RVGRHDNFFE LGGHSLLAVQ
MMERLRRLSL GVEVRTVFAK PMLADLAASL GSHREVAVPA NPITEQSTAI TPQMLPLIDL
TQPEIDRIVS TVPGGVGNIQ DIYGLSPLQD GILFHHLLAT QGDPYLLVSQ MAFAERGVLD
RYLAAVQQVV DRHDILRTAF VWEGLSSPAQ VVWRKAALDV LEVELEGCDG SGADELRRRF
DPRQYRLDLG RAPLMRFVIA REPGSGRWLL LVLQHHLIGD HTTAEVMHAE VRAVLQGRAH
ELAAPQPFRN LVAQARLGMD AKAHEAFFRE MLADIDESTL PFALSEVYGD GRGSREARRM
LPQALNDRLR HQARRLGVSL ASLCHLAWAQ VVALSSGREQ VVFGTVLFGR MHAGAGADRA
MGLFMNTLPL RLDLDETGVE ESVRIAHARL AELLSHEHAS LALAQRCSDI AAPAPLFSAL
LNYRHNTPAM AGEGTSDVLS GMEWLGDEER TNYPLTLSVD DFGQELGLTA DAVEPISADR
ICGYMQRALE QLVDALEQAP EQPVSELDIL PPDERSYLLE ELNRTETDYP SDLCVHALFE
AQVRRAPDAV ALVFEEQSIS YGALNADANR LAHHLIGLGV RPDQPVAICV ERSPAMVVGL
LAILKAGGAY VPLDPAYPSE RLRQLLDDAG PRLLLCDAAG RAALGAEAIA DLSAVDLDTA
TAWADQSADD PDPHALGLTA RNLAYVIYTS GSTGTPKGVM VEHQHLSNYL QWSNRSFYKR
TSNGSPVTHS MSFDGIVTTL FGPLLAGTKL HLLDPTVQII SLGELKKGQA FDLVKVTPSH
LSILNKKIDD DEGQPPTKAL MVGGEALVPA DMQLWQRRFP NVRLINHFGP TEATVGCAAF
EITGDVEGLT SIPIGRPIAN TRIYLLDGHG QPVPFGAVGE LYIGGAGVAR GYLNRPDLTA
ERFLADPFSG KAGARMYRSG DLARYLPDGN LEFLGRNDDQ VKIRGFRIEP GEIAARLLEH
ELVGDAAVVA HADAAGDKRL VAYVVAKTTD GSAEADGAGL AASLRAHLGG LLPDYMVPSA
FVRLDALPLT VNGKLDRKAL PVPDDDAYAR RAYEAPQGEI ETLLAGIWAE LLGVERVGRH
DNFFELGGHS LLTVQMMERL RRLSLGVEVR TVFAKPMLAD LAASLGSHRE VAVPANPITE
QSTAITPQML PLIDLTQPEI DRIVSTVPGG VGNIQDIYGL SPLQDGILFH HLLATQGDPY
LLVSQMAFAE RGVLDRYLAA VQQVVDRHDI LRTAFVWEGL SSPAQVVWRK AALDVLEVEL
EGCDGSGADE LRRRFDPRQY RLDLGRAPLM RFVIAREPGS GRWLLLVLQH HLIGDHTTAE
VMHAEVRAVL QGRAHELAAP QPFRNLVAQA RLGMDAKAHE AFFREMLADI DESTLPFALS
EVYGDGRGSR EARRMLPQAL NDRLRHQARR LGVSLASLCH LAWAQVVALS SGREQVVFGT
VLFGRMHAGA GADRAMGLFM NTLPLRLDLD ETGVEESVRI AHARLAELLS HEHASLALAQ
RCSDIAAPAP LFSALLNYRH NTPAMAGEGT SDVLSGMEWL GGEERTNYPL TLSVDDFGQE
LGLTADAVEP ISADRICGYM QRALEQLVDA LEQAPDRPVR ELDILPAEER SYLLEELNRT
EADYPSDLCV HALFEAQVRR APDAVALVFE EQSISYGALN ADANRLAYHL IGLGVRPDQP
VAICVERSPA MVVGLLAILK AGGAYVPLDP AYPSERLRQL LDDAGPRLLL CDAAGRAALG
AEAIADLSAV DLDAATAWAD QSADDPDPHA LGLTARNLAY VIYTSGSTGT PKGVMVEHRN
TVNLLHWSGG VFAESEIRRT LFSTSVCFDL SVYECFLPLS QGSKLYLVED ALKLARTPVD
ASLINTVPSA ITALVNQKAV PASASVINLA GERVKADLIE RIFESTRVQK ICNLYAPSET
TTYSTWICMP RGQAVVETIG RPIANTRIYL LDGHGQPVPF GAVGELYIGG AGVARGYLNR
PDLTAERFLA DPFSGKAGAR MYRSGDLARY LPDGNLEFLG RNDDQVKIRG FRIEPGEIAA
RLLEHELVGD AAVVAHADAA GDKRLVAYVV AKTTDGSAEA DGAGLAASLR AHLGGLLPDY
MVPSAFVRLD ALPLTVNGKL DRKALPVPDD DAYARRAYEA PQGEIETLLA GIWAELLGVE
RVGRHDNFFE LGGHSLLAVQ MMERLRRLSL GVEVRTVFAK PMLADLAASL GSHREVAVPA
NPITEQSTAI TPQMLPLIDL TQPEIDRIVS TVPGGVGNIQ DIYGLSPLQD GILFHHLLAT
QGDPYLLVSQ MAFAERGVLD RYLAAVQQVV DRHDILRTAF VWEGLSSPAQ VVWRKAALDV
LEVELEGCDG SGADELRRRF DPRQYRLDLG RAPLMRFVIA REPGSGRWLL LVLQHHLIGD
HTTAEVMHAE VRAVLQGRAH ELAAPQPFRN LVAQARLGMD AKAHEAFFRE MLADIDEPTL
PFALSEVYGD GRGSREARRM LPQALNDRLR HQARRLGVSL ASLCHLAWAQ VVALSSGREQ
VVFGTVLFGR MHAGAGADRA MGLFVNTLPL RLDLDETGVE ESVRIAHARL AELLSHEHAS
LALAQRCSDI AAPAPLFSAL LNYRHNTPAM AGEGTSDVLS GMEWLGGEER TNYPLTLSVD
DFGQELGLTA DAVEPISADR ICGYMQRALE QLVDALEQAP DRPVRELDIL PAEERSYLLE
ELNRTETDYP SDLCVHALFE AQVRRAPDAV ALVFEEQSIS YGALNADANR LAYHLIGLGV
RPDQPVAICV ERSPAMVVGL LAILKAGGAY VPLDPAYPSE RLRQLLDDAR PRLLLCDAAG
RAALGAEAIA DLSAVDLDAA TAWADQSADD PDPHALGLTA RNLAYVIYTS GSTGTPKGVM
VEHRNTVNLL HWSGGVFAES EIRRTLFSTS VCFDLSVYEC FLPLSQGSKL YLVEDALKLA
RTPVDASLIN TVPSAITALV NQKAVPASAS VINLAGERVK ADLIERIFES TRVQKICNLY
APSETTTYST WICMPRGQAV VETIGRPIAN TRIYLLDGHG QPVPFGAVGE LYIGGAGVAR
GYLNRPDLTA ERFLADPFSG KAGARMYRSG DLARYLPDGN LEFLGRNDDQ VKIRGFRIEP
GEIAARLLEH ELVGDAAVVA HADAAGDKRL VAYVIAKTTD GSAEADGAGL AASLRAHLGG
LLPDYMVPSA FVRLDALPLT VNGKLDRKAL PVPDDDAYAR RAYEAPQGEI ETLLAGIWAE
LLGVERVGRH DNFFELGGHS LLTVQMMERL RRLSLGVEVR TVFAKPMLAD LAASLGSHRE
VAVPANPITE QSTAITPQML PLIDLTQPEI DRIVSTVPGG VGNIQDIYGL SPLQDGILFH
HLLATQGDPY LLVSQMAFAE RGVLDRYLAA VQQVVDRHDI LRTAFVWEGL SSPAQVVWRK
AALDVLEVEL EGCDGSGADE LRRRFDPRQY RLDLGRAPLM RFVIAREPGS GRWLLLVLQH
HLIGDHTTAE VMHAEVRAVL QGRAHELAAP QPFRNLVAQA RLGMDAKAHE AFFREMLADI
DEPTLPFALS EVYGDGRGSR EARRMLPQAL NDRLRHQARR LGVSLASLCH LAWAQVVALS
SGREQVVFGT VLFGRMHAGA GADRAMGLFM NTLPLRLDLD ETGVEESVRI AHARLAELLS
HEHASLALAQ RCSDIAAPAP LFSALLNYRH NTPAMAGEGT SDVLSGMEWL GDEERTNYPL
TLSVDDFGQE LGLTADAVEP ISADRICGYM QRALEQLVDA LEQAPDRPVR ELDILPAEER
SYLLEELNRT ETDYPSDLCV HALFEAQVRR APDAVALVFE EQSISYGALN ADANRLAYHL
IGLGVRPDQP VAICVERSPA MVVGLLAILK AGGAYVPLDP AYPSERLRQL LDDARPRLLL
CDAAGRAALG AEAIADLSAV DLDAATAWAD QSADDPDPHA LGLTARNLAY VIYTSGSTGT
PKGVMVEHAS VLNVLRALLD VSGLTERDSF LAITTISFDI AGLELYLPLA VGANVVVAHG
ASAIGLQRYL SHQKITVMQA TPAAWRMLFD AGWEGAPDLS ALCGGEALPS ELASNLGRRV
KSLRNLYGPT ETTIWATTFL TDTRIEAPHR YVPIGRPIAN TRIYLLDGHG QPVPFGAVGE
LYIGGAGVAR GYLNRPDLTA ERFLADPFSG KAGARMYRSG DLARYLPDGN LEFLGRNDDQ
VKIRGFRIEP GEIAARLLEH ELVGDAAVVA HADAAGDKRL VAYVVAKTTD GSAEADGAGL
AASLRAHLGG LLPDYMVPSA FVRLDALPLT VNGKLDRKAL PVPDDDAYAR RAYEAPQGEI
ETLLAGIWAE LLGVERVGRH DNFFELGGHS LLAVQMMERL RRLSLGVEVR TVFAKPMLAD
LAASLGSHRE VAVPANPITE QSTAITPQML PLIDLTQPEI DRIVSTVPGG VGNIQDIYGL
SPLQDGILFH HLLATQGDPY LLVSQMAFAE RGVLDRYLAA VQQVVDRHDI LRTAFVWEGL
SSPAQVVWRK AALDVLEVEL EGCDGSGADE LRRRFDPRQY RLDLGRAPLM RFVIAREPGS
GRWLLLVLQH HLIGDHTTAE VMHAEVRAVL QGRAHELAAP QPFRNLVAQA RLGMDAKAHE
AFFREMLADI DEPTLPFALS EVYGDGRGSR EARRMLPQAL NDRLRHQARR LGVSLASLCH
LAWAQVVALS SGREQVVFGT VLFGRMHAGA GADRAMGLFM NTLPLRLDLD ETGVEESVRI
AHARLAELLS HEHASLALAQ RCSDIAAPAP LFGALLNYRH NTPAMAGEGT SDVLSGMEWL
GGEERTNYPL TLSVDDFGQE LGLTADAVEP ISADQICGYM QRALEQLVDA LEQAPDRPVR
ELDILPAEER SYLLEELNRT ETDYPSDLCV HALFEAQVRR APDAVALVFE EQSISYGALN
ADANRLAYHL IGLGVRPDQP VAICVERSPA MVVGLLAILK AGGAYVPLDP AYPSERLRQL
LDDARPRLLL CDAAGRAALG AEAIADLSAV DLDAATAWAD QSADDPDPHA LGLTARNLAY
VIYTSGSTGT PKGVMVEHRN TVNLLHWSGG VFAESEIRRT LFSTSVCFDL SVYECFLPLS
QGSKLYLVED ALKLARTPVD ASLINTVPSA ITALVNQKAV PASASVINLA GERVKADLIE
RIFESTRVQK ICNLYAPSET TTYSTWICMP RGQAVVETIG RPIANTRIYL LDGHGQPVPF
GAVGELYIGG AGVARGYLNR PDLTAERFLA DPFSGKAGAR MYRSGDLARY LPDGNLEFLG
RNDDQVKIRG FRIEPGEIAA RLLEHELVGD AAVVAHADAA GDKRLVAYVV AKTTDGSAEA
DGAGLAASLR AHLGGLLPDY MVPSAFVRLD ALPLTVNGKL DRKALPVPDD DAYARRAYEA
PQGEIETLLA GIWAELLGVE RVGRHDNFFE LGGHSLLAVR VLVRLTEALA VELPLAMLFA
KPTLAELARE SSISLIAQEF DSHELQKLLS SRSLK
//
