ID A6W466_KINRD Unreviewed; 406 AA.
AC A6W466;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Periplasmic binding protein/LacI transcriptional regulator {ECO:0000313|EMBL:ABS01605.1};
GN OrderedLocusNames=Krad_0114 {ECO:0000313|EMBL:ABS01605.1};
OS Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216).
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Kineococcus.
OX NCBI_TaxID=266940 {ECO:0000313|EMBL:ABS01605.1, ECO:0000313|Proteomes:UP000001116};
RN [1] {ECO:0000313|Proteomes:UP000001116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-149 / DSM 14245 / SRS30216
RC {ECO:0000313|Proteomes:UP000001116};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J.,
RA Fliermans C., Richardson P.;
RT "Complete sequence of chromosome of Kineococcus radiotolerans SRS30216.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000750; ABS01605.1; -; Genomic_DNA.
DR AlphaFoldDB; A6W466; -.
DR STRING; 266940.Krad_0114; -.
DR KEGG; kra:Krad_0114; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_4_11; -.
DR Proteomes; UP000001116; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 2.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 2.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 2.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 2.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 2.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001116};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 70..124
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 406 AA; 43093 MW; 9656359700CD29FD CRC64;
MGSTRTARGR GGAPSMVEVA ALAGVSVGTV SNVVNHPERV RAETIEKVRA AIEQLGFSRA
VPVRAARTNP SVVEVAAVAG VSVGTVSNAL NHPEQVRPET LARVRAAIEQ LGFTPNANAR
SLAGGENRTI GLVVVDLGNT LFVDIARGAQ REAAARGESL LVTNSDRDDA QQDAHLDLFE
SARVRGVVLA PLSDPFAGIQ RVRRHGTPLV VVNYDDGRQD CCTVLVDNER VGYLAARHMV
ELGRRRLAWV SELNDLQPVH ERQAGVRRAV REAGRGVSLV ELDTEGVGEN DGDHVVEEVL
ALPARRRPDA LIAVTDMLGA SVVEALRGAG LSVPGDIAVM GCDHDARAWG GAVPLTTVRM
EGEEMGAAAV RLLADEVAEG VDHVHRRVVV QPSLLVRESS AGRLPR
//
