ID A7AQC3_BABBO Unreviewed; 339 AA.
AC A7AQC3;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Adenosine kinase {ECO:0000313|EMBL:EDO06742.1};
DE EC=2.7.1.25 {ECO:0000313|EMBL:EDO06742.1};
GN ORFNames=BBOV_IV003810 {ECO:0000313|EMBL:EDO06742.1};
OS Babesia bovis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5865 {ECO:0000313|EMBL:EDO06742.1, ECO:0000313|Proteomes:UP000002173};
RN [1] {ECO:0000313|EMBL:EDO06742.1, ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO06742.1};
RX PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H., Koo H.,
RA Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q., Smith R.K. Jr.,
RA Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr., McElwain T.F.,
RA Nene V.M.;
RT "Genome sequence of Babesia bovis and comparative analysis of apicomplexan
RT hemoprotozoa.";
RL PLoS Pathog. 3:1401-1413(2007).
RN [2] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33294524; DOI=10.1016/j.dib.2020.106533;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Transcriptome dataset of Babesia bovis life stages within vertebrate and
RT invertebrate hosts.";
RL Data Brief 33:106533-106533(2020).
RN [3] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33069745;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Comparative analysis of gene expression between Babesia bovis blood stages
RT and kinetes allowed by improved genome annotation.";
RL Int. J. Parasitol. 51:123-136(2021).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO06742.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAXT01000002; EDO06742.1; -; Genomic_DNA.
DR RefSeq; XP_001610310.1; XM_001610260.1.
DR AlphaFoldDB; A7AQC3; -.
DR STRING; 5865.A7AQC3; -.
DR EnsemblProtists; EDO06742; EDO06742; BBOV_IV003810.
DR GeneID; 5478569; -.
DR KEGG; bbo:BBOV_IV003810; -.
DR VEuPathDB; PiroplasmaDB:BBOV_IV003810; -.
DR eggNOG; KOG2854; Eukaryota.
DR InParanoid; A7AQC3; -.
DR Proteomes; UP000002173; Unassembled WGS sequence.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01168; adenosine_kinase; 1.
DR Gene3D; 3.30.1110.10; -; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43320:SF3; CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43320; SUGAR KINASE; 1.
DR Pfam; PF00294; PfkB; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EDO06742.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002173};
KW Transferase {ECO:0000313|EMBL:EDO06742.1}.
FT DOMAIN 62..312
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 339 AA; 37251 MW; 6BDE3FB6BCCD7666 CRC64;
MADVIMHHGN ASVLFIGHPM MDMFARVDDS VVERFSVPKG ESNIVSQEVF DELNSMIKLE
KVTPGGLSST MAFAYLGGIV SFFGIVGDDA YGKQFYKAVK SQGVKMYTPF RKGVPTSRLL
SLITPDHERT MYLSMGASHT LTVNDIKPSI MDKHDYFAVN GFVFSGPDQV IFTNMMVGES
LRRGKGVITL IANPFCVRVN GHFLKPIIDR SEYVSGNIEE YSNLYNMHDR SELRKYLASR
TAGETPINKA IILTLGPEGA IIFHHGEEFF IPAAECDVVD TTGAGDFFAG SVLYGMLNGY
TLQKSGEFAR VIVGDLISHI GCTLSPEVRA KVDAIKMEA
//
