ID A7BAI8_9ACTO Unreviewed; 1274 AA.
AC A7BAI8;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Peptidase, S8/S53 family {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACTODO_00652 {ECO:0000313|EMBL:EDN80212.1};
OS Schaalia odontolytica ATCC 17982.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Schaalia.
OX NCBI_TaxID=411466 {ECO:0000313|EMBL:EDN80212.1, ECO:0000313|Proteomes:UP000003553};
RN [1] {ECO:0000313|EMBL:EDN80212.1, ECO:0000313|Proteomes:UP000003553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17982 {ECO:0000313|EMBL:EDN80212.1,
RC ECO:0000313|Proteomes:UP000003553};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDN80212.1, ECO:0000313|Proteomes:UP000003553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17982 {ECO:0000313|EMBL:EDN80212.1,
RC ECO:0000313|Proteomes:UP000003553};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Actinomyces odontolyticus (ATCC 17982).";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDN80212.1}.
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DR EMBL; AAYI02000004; EDN80212.1; -; Genomic_DNA.
DR RefSeq; WP_003791214.1; NZ_DS264586.1.
DR AlphaFoldDB; A7BAI8; -.
DR eggNOG; COG1404; Bacteria.
DR eggNOG; COG5263; Bacteria.
DR HOGENOM; CLU_006694_0_0_11; -.
DR Proteomes; UP000003553; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07475; Peptidases_S8_C5a_Peptidase; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 2.10.270.10; Cholin Binding; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR Gene3D; 2.60.40.1710; Subtilisin-like superfamily; 1.
DR InterPro; IPR034216; C5a_Peptidase.
DR InterPro; IPR018337; Cell_wall/Cho-bd_repeat.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF01473; Choline_bind_1; 1.
DR Pfam; PF19127; Choline_bind_3; 3.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF69360; Cell wall binding repeat; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51170; CW; 3.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1274
FT /note="Peptidase, S8/S53 family"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002705212"
FT DOMAIN 195..663
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 467..532
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 699..816
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT REPEAT 1193..1212
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 1213..1232
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 1233..1252
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REGION 27..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 204
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 271
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 598
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1274 AA; 132263 MW; E5634CB1CEC2B2D7 CRC64;
MTTKKPATLL ALAGTAALVV AGPAALASPQ TPADTRPDAG ATASSLPVGD VDTALTSKSG
ETTQTEQAPT TDEVDPAAVV TIVVQLDDGA DRAASLASIN EAVAGAFPGS STQVEREYDK
ALQGFALSAP AGSLDAIRAV NGVKAAFLDR DTHVDGVDDQ VAGEGATNSS RIATQDPANL
SAQLMIHADQ ITQKGDGKVV AVIDTGVDMT HPAFAGALHG TPGLSEDKVE ALTPQLGDGK
TGSYVSEKFP FAYDYADNDP DASPTGEAGS HGTHVAGITA GNAGEIVGIA PDAQIIVAKV
ARSSNGGIPD SALLAALDDM VILHPDVVNL SLGQTGGMDN EADSMYATVF KSLQDAGVTV
NAAAGNEYTA GYGNLSGKNL PFASDPDSSV LCEPASYSSV VSVASVDNSL AHSAFTVGDR
DIAYQRAGGA DGQKMPDLSD LTGGPFEYVD GGIGSPEDGE ALKAKYPEGL AGKIVLVKRG
SLTFQDKFNN IAGSKPAGFI VYNNVPGDSL VVMSLATDGV PAAFISQADG EAMLAAADHH
LSVAPGKVVP PSSKYSMSSF SSWGVTPDLR LKPEVSAPGG NIYSAVPGGT YEFMSGTSMA
TPQMAGVSAV VLQRVQNDPL FASMSAREKV DVVQNLIMST AAPIVDPLQD TGAPYSPRKQ
GSGLANVLAA TTSSVYPTVV GAPEQSRPKA DLGDGTKGWH FDVTLHNLSG AEATYELSSQ
ALSEIVEGGF FTGHSADWRG KGVDIAYSGA AVSGTDEGAI ITVPANGEAT VGVDVKPGTD
FDASIAQNMP NGTFLDGFVR FTSKTASQPD LTVPYLGFYG NWGKAPIFDA LASEDGAHTL
ASWVYNGTTG QQLGYNPLVK DADRIGLPTS SKNVISRSDA SGAPTVLQPR TGTLRSVHTL
NAAYTNAAGE TVASFTRFMN WKSALDSSTG KMTWVEQGHD PMSLDARADA YKNLPDGTYK
LTLSAHNDGP SQADQSISYE FRLDTAAPVV SNLEYKGEGA DTVLSFDITD ASLLAAIDLH
DPADGLWFYR HIFTDNEATT AADGTRAYHV EIPFKDIAQA WTDQGGSGEV IAHPYLLAWD
YGLNHSEALT LNLPSDNTGT ADACASTEGG HWTKDAAGWF YTCADGTSYL KGGWYTINGS
DYLFGPSGYM ATGFLKRADG QWVYANESGA LVGGWVRDGG SWYYLDPTTK VMATGWVADG
GSWYYLTSSG AMAIGWVQVD GSWYYLSGSG TMATGWIKVG GLWYYLGPDG AMLTGTQVIN
GRTYVFDGSG VWVG
//
