ID A7DWM5_SORMA Unreviewed; 167 AA.
AC A7DWM5;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 22-FEB-2023, entry version 37.
DE SubName: Full=Putative scytalone dehydratase {ECO:0000313|EMBL:CAM35473.1};
GN Name=sdh {ECO:0000313|EMBL:CAM35473.1};
OS Sordaria macrospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=5147 {ECO:0000313|EMBL:CAM35473.1};
RN [1] {ECO:0000313|EMBL:CAM35473.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=K-hell 48977 {ECO:0000313|EMBL:CAM35473.1};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CAM35473.1};
RX PubMed=17681008; DOI=10.1111/j.1574-6968.2007.00867.x;
RA Engh I., Nowrousian M., Kuck U.;
RT "Regulation of melanin biosynthesis via the dihydroxynaphthalene pathway is
RT dependent on sexual development in the ascomycete Sordaria macrospora.";
RL FEMS Microbiol. Lett. 275:62-70(2007).
CC -!- SIMILARITY: Belongs to the scytalone dehydratase family.
CC {ECO:0000256|ARBA:ARBA00008584, ECO:0000256|PIRNR:PIRNR024851}.
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DR EMBL; AM493726; CAM35473.1; -; Genomic_DNA.
DR AlphaFoldDB; A7DWM5; -.
DR VEuPathDB; FungiDB:SMAC_02101; -.
DR GO; GO:0030411; F:scytalone dehydratase activity; IEA:InterPro.
DR GO; GO:0006582; P:melanin metabolic process; IEA:InterPro.
DR Gene3D; 3.10.450.50; -; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR004235; Scytalone_dehydratase.
DR Pfam; PF02982; Scytalone_dh; 1.
DR PIRSF; PIRSF024851; SCD1; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|PIRNR:PIRNR024851}.
FT ACT_SITE 85
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-50"
FT ACT_SITE 111
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-50"
FT BINDING 30
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-51"
FT BINDING 50
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-51"
FT BINDING 53
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-51"
FT BINDING 132
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR024851-51"
SQ SEQUENCE 167 AA; 19371 MW; A49301681981269C CRC64;
MANAANPKTR ITFEEYLGCT EACFEWADSY DSKDFDRLRK CIAPTLRVDY RSFLNKLWEA
MPAEEFIQMV SDKKVIGNPL LRTQHFMSGI SKWEKVSDTE IIGYHQLRVP HQVYTDKSCT
KVAVTGHAHS HNTHYYKKVD GVWKFAGLNP DIRWTEGDFD KVFADRA
//
