ID A7ECH3_SCLS1 Unreviewed; 1132 AA.
AC A7ECH3;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=SS1G_03012 {ECO:0000313|EMBL:EDO00152.1};
OS Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS (Whetzelinia sclerotiorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=665079 {ECO:0000313|EMBL:EDO00152.1, ECO:0000313|Proteomes:UP000001312};
RN [1] {ECO:0000313|Proteomes:UP000001312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18683 / 1980 / Ss-1 {ECO:0000313|Proteomes:UP000001312};
RX PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
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DR EMBL; CH476623; EDO00152.1; -; Genomic_DNA.
DR RefSeq; XP_001596789.1; XM_001596739.1.
DR AlphaFoldDB; A7ECH3; -.
DR EnsemblFungi; EDO00152; EDO00152; SS1G_03012.
DR GeneID; 5492279; -.
DR KEGG; ssl:SS1G_03012; -.
DR eggNOG; KOG1075; Eukaryota.
DR HOGENOM; CLU_000680_23_0_1; -.
DR InParanoid; A7ECH3; -.
DR OMA; SWESSNC; -.
DR OrthoDB; 1804362at2759; -.
DR Proteomes; UP000001312; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001312}.
FT DOMAIN 371..644
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1132 AA; 127262 MW; 6C970981A37F60F8 CRC64;
MPPSPTRERK EIKIRTPDNP EDIPRKQKLY GNQAIKALFE LQNFPNNAIL LGDFNLHHPN
WNPLHPSPST LAEPFVEWSN SRNLHLISPI GTPTHSKGNV LDLTFLSGPY TAYTALAEQL
ECTSDHSTLK TYLHWNYRSQ KPAKKLKLNT LNETLFKDLL ETNLTNIAAI PRTPSLRDLD
QAASSLTQAL TKAYTGSARR SINGPLQQPW WNKDCIKAVY KHRITNTPTS KRSLRKTVRK
AKHTFYITKV DKVEDINDVY RMAKWHQSTG IYRTPPLADL SKQTIANTIE EKRETFANNL
LTNLAEVDDI PFDTPTAPSR SITFPDIAIQ DIELAILKAG NTAPGADEIP TKILQVAWLQ
IKEVTLSLFK GCLHLGHHPK CFRLATIVII PKPNKPDYTN PRSYRPIALL SVLGKGLERL
IAKKVSWLAL NYQVLANQQL GALPLRSSVD LTTCVTHDIE ASLKQGLKTT LLTMDVKGAF
DAVLPGRLVN RLREQGWPNN LVRWVQSFAT NRSIKIRLDG ETGPETKLEC GLPQGSPISP
ILFMLYIAPL FWMGKPQSRF GYADDIAILA TSNSLQTNCD SLKMDMQETL EWGKTEGITF
DPKKSELIHF YKGHRTLTDT PAIHTGSMNI EVKPGPLKWL GVHFDRKLCF KPHVQILAAK
ALKGANALRS LSNTHRGIPP YLTRKVAEAC ILKKCYFASE TWWPGRTRTK KNALNNPISI
SNVVDSHLSL LNKVVITCTR AILPVYKTTN TAVLYEEAKL RPSEIELNLI SQLYAARTTR
LDLYHPLRIR AENITKAREY NRTPDTRFAR LITALPETEH INPLAFPPWE IRESRAEAEA
RINGPMGRTK AQAAEDFKAF HAKIPRSDIQ IFSDGSKSES KDGATGGGFV ISQFDIQIAH
HSFSLGTNAE VFDAEATAAV AGAAKALTLA STKLATDLWI FLDNHEAALR LGSHFNGSSQ
RVFEDFLKLT QAWAEGTKLP FPLNPICTLA SLKRMIRTRA NKADEQLWNT VSPQYYKDLQ
FNHTSNTDTL SLKRATLHHI LAIRSQHGDF AAYHERFNHT TAHVHCSCGK RKTPLHFFFC
KKGKAFKALT KSPPSEAIPW LLRNPTGIAK LAEWLEYTKF YTKICPWHTG AR
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