ID A7H0X9_CAMC5 Unreviewed; 300 AA.
AC A7H0X9;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Geranyl diphosphate synthase / farnesyl diphosphate synthase {ECO:0000313|EMBL:EAU00317.2};
DE EC=2.5.1.1 {ECO:0000313|EMBL:EAU00317.2};
DE EC=2.5.1.10 {ECO:0000313|EMBL:EAU00317.2};
GN Name=ispA {ECO:0000313|EMBL:EAU00317.2};
GN ORFNames=CCV52592_0071 {ECO:0000313|EMBL:EAU00317.2};
OS Campylobacter curvus (strain 525.92).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=360105 {ECO:0000313|EMBL:EAU00317.2, ECO:0000313|Proteomes:UP000006380};
RN [1] {ECO:0000313|Proteomes:UP000006380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=525.92 {ECO:0000313|Proteomes:UP000006380};
RA Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G.,
RA Mandrell R.E., Lastovica A.J., Nelson K.E.;
RT "Genome sequence of Campylobacter curvus 525.92 isolated from human
RT feces.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000767; EAU00317.2; -; Genomic_DNA.
DR AlphaFoldDB; A7H0X9; -.
DR STRING; 360105.CCV52592_0071; -.
DR KEGG; ccv:CCV52592_0071; -.
DR HOGENOM; CLU_014015_0_1_7; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000006380; Chromosome.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000006380};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:EAU00317.2}.
SQ SEQUENCE 300 AA; 32718 MW; FB27A07B20558BCB CRC64;
MTLLDEFIKF LNANLPKAPS FHPYYEEALG VMLKAGGKHF RAQLLLGVVD ALRPQLTQNA
MRVALGLEMM HTYSLIHDDL PAMDDAPLRR GVPTLHTRYD EVTAILAGDA LNTQAFYEIS
RADLEAPVVV KCVEILSANA GASGMVLGQA LDCFFENSDK ADVKNAKNRL GLAQKRLNLD
ELEFLHIHKT AKLIAASLEM GAVIAALDAA QCERIYGIGL DLGLAFQIED DLIDATSDES
EAGKPVHNDV TKNSFTNLLG IDGARASKNE LIAKIRRELS DMPKGVCNVV ENLIDKHLKG
//
