ID A7IWS4_PBCVN Unreviewed; 260 AA.
AC A7IWS4;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 13-SEP-2023, entry version 58.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN Name=B399R {ECO:0000313|EMBL:ABT14798.1};
GN ORFNames=NY2A_B399R {ECO:0000313|EMBL:ABT14798.1};
OS Paramecium bursaria Chlorella virus NY2A (PBCV-NY2A).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Algavirales; Phycodnaviridae; Chlorovirus.
OX NCBI_TaxID=46021 {ECO:0000313|EMBL:ABT14798.1, ECO:0000313|Proteomes:UP000202419};
OH NCBI_TaxID=3071; Chlorella.
RN [1] {ECO:0000313|EMBL:ABT14798.1, ECO:0000313|Proteomes:UP000202419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NY-2A {ECO:0000313|EMBL:ABT14798.1,
RC ECO:0000313|Proteomes:UP000202419};
RX PubMed=17027058; DOI=10.1016/j.virol.2006.08.033;
RA Fitzgerald L.A., Graves M.V., Li X., Feldblyum T., Nierman W.C.,
RA Van Etten J.L.;
RT "Sequence and annotation of the 369-kb NY-2A and the 345-kb AR158 viruses
RT that infect Chlorella NC64A.";
RL Virology 358:472-484(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; DQ491002; ABT14798.1; -; Genomic_DNA.
DR RefSeq; YP_001497595.1; NC_009898.1.
DR REBASE; 3108; M.CviQVI.
DR GeneID; 5658897; -.
DR KEGG; vg:5658897; -.
DR OrthoDB; 8399at10239; -.
DR Proteomes; UP000202419; Genome.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.1020.10; Adenine-specific Methyltransferase, Domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR023095; Ade_MeTrfase_dom_2.
DR InterPro; IPR012263; M_m6A_EcoRV.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00571; dam; 1.
DR PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR Pfam; PF02086; MethyltransfD12; 1.
DR PIRSF; PIRSF000398; M_m6A_EcoRV; 1.
DR PRINTS; PR00505; D12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000202419};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 260 AA; 30965 MW; E6CBFF7BAB16096F CRC64;
MKPIVKWSGG KSDELKRFEE YIPSDCSTFI EPFAGGAATF FHVGERFENR VISDVHTELI
ALYRAIADGR SREIYDFMKT HANDEKTYYE VRNWRPEDYV GVANRFYYLR KTCFRGMMRY
NRNGGFNVPF GRYKTYNFED ILDEKYHILL KDTTILEKSF DYIFETYNDI DNFVFLDPPY
DSVFTDYGYC SFGKEEHIRL ANHFKSTKNK CLMIIGATDF IRDLYDGYIV DEYDKKYRFK
LHSGRVGDEI NTKHLIIKNY
//
