ID A7J9Q3_HBV Unreviewed; 280 AA.
AC A7J9Q3;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 14-DEC-2022, entry version 48.
DE SubName: Full=Polymerase {ECO:0000313|EMBL:ABJ80625.1};
DE Flags: Fragment;
GN Name=P {ECO:0000313|EMBL:ABJ80625.1};
OS Hepatitis B virus (HBV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=10407 {ECO:0000313|EMBL:ABJ80625.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1] {ECO:0000313|EMBL:ABJ80625.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pts33_Bas {ECO:0000313|EMBL:ABJ80625.1};
RX PubMed=17567633; DOI=10.1093/jac/dkm187;
RA Moriconi F., Colombatto P., Coco B., Ciccorossi P., Oliveri F.,
RA Flichman D., Maina A.M., Sacco R., Bonino F., Brunetto M.R.;
RT "Emergence of hepatitis B virus quasispecies with lower susceptibility to
RT nucleos(t)ide analogues during lamivudine treatment.";
RL J. Antimicrob. Chemother. 60:341-349(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ995841; ABJ80625.1; -; Genomic_DNA.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..252
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABJ80625.1"
FT NON_TER 280
FT /evidence="ECO:0000313|EMBL:ABJ80625.1"
SQ SEQUENCE 280 AA; 31522 MW; 20E935A8BC9A8FE2 CRC64;
WGPCAEHGEH HIRIPRTPSR VTGGVFLVDK NPHNTAESRL VVDFSQFSRG XYRVSWPKFA
VPNLQSLTNL LSSNLSWLSL DVSAAFYHIP LHPAAMPHLL VGSSGLSRYV ARLSSNSRIL
NHQHGTMPHL HDSCSRNLYD SLLLLYQTFG RKLHLYSHPI ILGFRKIPMG VGLSPFLMAQ
FTSAICSVVR RAFPHCLAFS YVDDVVLGAK SVQHLESLFT AVTNFLLSLG IHLNPNKTKR
WGYSLNFMGY VIGCYGSLPQ EHIKQKIKEC FRKLPINRPI
//
