ID A7RFP0_NEMVE Unreviewed; 791 AA.
AC A7RFP0;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
GN ORFNames=NEMVEDRAFT_v1g196494 {ECO:0000313|EMBL:EDO49636.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO49636.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO49636.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469508; EDO49636.1; -; Genomic_DNA.
DR RefSeq; XP_001641699.1; XM_001641649.1.
DR AlphaFoldDB; A7RFP0; -.
DR STRING; 45351.A7RFP0; -.
DR EnsemblMetazoa; EDO49636; EDO49636; NEMVEDRAFT_v1g196494.
DR eggNOG; KOG3684; Eukaryota.
DR HOGENOM; CLU_355012_0_0_1; -.
DR InParanoid; A7RFP0; -.
DR PhylomeDB; A7RFP0; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 412..463
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 90200 MW; 5799374D6A4E55E9 CRC64;
MESSETRSRS LSTSDRYELN HLNSSPNGKS DMNRYRRTNS SVTPGTFGNF TRTGSQKRSM
RSSIRSDMPS FDQTLRSFRD IDTAKKFFHR RIRILSGLSC LMGVSAVVLA IIDIEIAKHR
REKLLNGQLQ VADSLSASKD AFGIAGIVLK AAISLFSLLT CITIFNIYSN TRKLNVVKNL
FHESESFLTS RTLLPRFLLE TLICLTHIPP YVDDLGIPYK LQLLVFIRLY LLTRCLRERS
KFFNNQATSL LASVTKTEIS STFLVKTYFL KEPFKLIFSF YTMNIFLGGY CVYVIEDSHP
YLKKIKSLLD LFAKPAYSSH FQIISEVNKY AISVTIFERA QGLVKRYTTR VHVKNNKIIP
RLEYHGPLNR KALKDMRSCK KVLLKITQGV INCRTKYYGD AKMVKAIYCV KDTVWMMVVT
MTTLGFGDIV PVSVVARGLV GFASILGIFL MALFISVVHE YLQLTNQEKR ILAYIEKADH
QQEKMEKAAA CIQSCWRYRQ FVKRHMKSLE LGDWLKLQRM RFLQHKLFEC MRQWRGMRRT
WARDDYWRKL FVVDDTAMLL TDVCRSVTNI EKCLHIPPAS RKRSSSRPSL SRHASYGSPP
ARIREEDALE RPPVSPNVFP PISPSREKAN SLQTVLVESL ETRDKPEKRI SNPAIQVVAL
PREIPRICAN HTGISPANKT DRDFDRNKRA FLNRPQAARK ASDLSTSSDH IDRGAMTFDM
LQSRIEGVES ALDQIYGKVK SELRDIKDTV STMAAAGHFN TPSSSPGALP SQVGSTSDPL
FSYATMDKYD I
//
